Results 51 to 60 of about 1,012,225 (263)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Performance enhancement of an axial flow compressor using active flow control technique

Cogent Engineering
This research article focuses on improving the efficiency of an axial flow compressor stage, enhancing the stall margin, and optimizing flow parameters.
Prithesh Pinto, Srinivas G
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Designs of Feedback Controllers for Fluid Flows Based On Model Predictive Control and Regression Analysis

Energies, 2020
Complexity of online computation is a drawback of model predictive control (MPC) when applied to the Navier−Stokes equations. To reduce the computational complexity, we propose a method to approximate the MPC with an explicit control law by using ...
Yasuo Sasaki, Daisuke Tsubakino
doaj   +1 more source

Active Flow Control for Helicopters

, 2013
Several active flow control helicopter applications aimed at improving aerodynamic performance have been studied at Onera and are presented in this paper. The distinction between applications for non-rotating or non-lifting parts and for rotating parts is presented.
Le Pape, A., Lienard, C., Bailly, J.
openaire   +2 more sources

Transitioning active flow control to applications [PDF]

30th Fluid Dynamics Conference, 1999
Active Flow Control Programs at NASA, the U.S. Air Force, and DARPA have been initiated with the goals of obtaining revolutionary advances in aerodynamic performance and maneuvering compared to conventional approaches. These programs envision the use of actuators, sensors, and controllers on applications such as aircraft wings/tails, engine nacelles ...
Ronald Joslin, Lucas Horta, Fang-Jenq Chen   +2 more
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Synthetic Jet Actuators for Active Flow Control: A Review

Fluids
A synthetic jet actuator (SJA) is a fluidic device often consisting of a vibrating diaphragm that alters the volume of a cavity to produce a synthesized jet through an orifice.
Howard H. Ho, Ali Shirinzad, Ebenezer E. Essel, Pierre E. Sullivan   +3 more
doaj   +1 more source

Wall Shear Stress Calorimetric Micro-Sensor Designed for Flow Separation Detection and Active Flow Control

Proceedings, 2017
This paper presents an efficient and high-sensitive micro-sensor designed for wall shear stress measurement. The main technical application targeted is flow separation detection for closed-loop active flow control.
Cécile Ghouila-Houri, Quentin Gallas, Eric Garnier, Alain Merlen, Romain Viard, Abdelkrim Talbi, Philippe Pernod   +6 more
doaj   +1 more source