Results 61 to 70 of about 1,012,225 (263)

In-sewer sedimentation associated with active flow control

open access: yesWater Science and Technology, 2009
Active flow control using automated gates and weirs aims to utilise available dispersed storage within sewer systems to alleviate the severity and frequency of localised flooding incidents. Whilst a previous study has demonstrated its potential, a key operational concern before implementation was sedimentation. An experimental programme was designed to
K J, Williams, S J, Tait, R M, Ashley
openaire   +2 more sources

Light-controlled flows in active fluids [PDF]

open access: yesNature Physics, 2016
The ability of phototactic microorganisms to move towards optimal light intensities is exploited to generate fluid flows on scales several orders larger than the swimmers themselves. These flows are shown to function as hydrodynamic tweezers.
Dervaux, Julien   +2 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Numerical Study of the Effect of Corona Discharge on Upward Wake Flow in the Horizontal Axis Wind Turbine Farm [PDF]

open access: yesJournal of Applied Fluid Mechanics
Many countries worldwide are showing a growing interest in renewable energy sources, with wind energy being a particularly appealing option for generating mechanical energy.
S. Abed Zahmatkesh Pasand   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

An Experimental Investigation by Particle Image Velocimetry of the Active Flow Control of the Stall Inception of an Axial Compressor

open access: yesInternational Journal of Turbomachinery, Propulsion and Power
This paper presents results from active flow control experiments carried out on a single stage axial compressor. The flow under various forced conditions has been investigated using 2D 2C particle image velocimetry (PIV) on three radial planes along the ...
Olha Alekseik   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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