Results 141 to 150 of about 2,971,967 (301)

Contribution à l'étude du contrôle actif de l’écoulement autour d’un profil de pale d’éolienne

Revue des Énergies Renouvelables, 2015
Cette étude a pour objectif l’amélioration des caractéristiques aérodynamiques d’un profil de pale d’éolienne par l’utilisation d’une technique de contrôle actif de l’écoulement.
A. Boudis, O. Guerri, A. Benzaoui, H. Oualli   +3 more
doaj  

Control of unsteady separated flow associated with the dynamic stall of airfoils [PDF]

The two principal objectives of this research were to achieve an improved understanding of the mechanisms involved in the onset and development of dynamic stall under compressible flow conditions, and to investigate the feasibility of employing adaptive ...
Wilder, Michael C.
core   +1 more source

Active Flow Control Activities at NASA Langley [PDF]

2nd AIAA Flow Control Conference, 2004
Scott Anders, William Sellers III, Anthony Washburn   +2 more
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Deep reinforcement learning for active flow control in a turbulent separation bubble. [PDF]

Nat Commun
Font B, Alcántara-Ávila F, Rabault J, Vinuesa R, Lehmkuhl O.   +4 more
europepmc   +2 more sources

Active stabilization to prevent surge in centrifugal compression systems [PDF]

This report documents an experimental and analytical study of the active stabilization of surge in a centrifugal engine. The aims of the research were to extend the operating range of a compressor as far as possible and to establish the theoretical ...
Epstein, Alan H., Greitzer, Edward M., Simon, Jon S., Valavani, Lena   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Numerical Investigation of Active Flow Control Around a Generic Truck A-Pillar. [PDF]

Flow Turbul Combust, 2016
Minelli G, Krajnović S, Basara B, Noack BR.   +3 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source