Results 41 to 50 of about 1,024,804 (310)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Systems and certification issues for civil transport aircraft flow control systems [PDF]

open access: yes, 2009
This article is placed here with permission from the Royal Aeronautical Society - Copyright @ 2009 Royal Aeronautical SocietyThe use of flow control (FC) technology on civil transport aircraft is seen as a potential means of providing a step change in ...
Crowther, W. J.; id_orcid   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Numerical Investigation of Supersonic Combustion Flow Control by Nanosecond-Pulsed Actuations

open access: yesEnergies, 2023
The efficiency of supersonic combustion is largely dependent on inlet and injection parameters. Additional energy input is required in some off-design conditions, and nanosecond discharge actuation can be a solution.
Yilun Yan   +3 more
doaj   +1 more source

Parameter study for a slatless 2D high-lift airfoil with active separation control using a URANS approach

open access: yes, 2013
The numerical investigations described in the present paper deal with active flow separation control for a 2D, 2-element high-lift airfoil. Here, the aim of the flow control application is to actively reduce or eliminate a large flow separation on the ...
V. Ciobaca, Ciobaca, Vlad
core   +1 more source

The flow structure behind vortex generators embedded in a decelerating turbulent boundary layer [PDF]

open access: yes, 2009
The objective of the present work is to analyse the behaviour of a turbulent decelerating boundary layer under the effect of both passive and active jets vortex generators (VGs).
Braud, Caroline   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Wind Turbine Enhancement via Active Flow Control Implementation

open access: yesApplied Sciences
The present research enhances the efficiency of an airfoil section from the DTU-10MW Horizontal Axis Wind Turbine (HAWT) via Active Flow Control (AFC) implementation and when using synthetic jets (SJ).
Marc Lahoz   +3 more
doaj   +1 more source

Stall Margin Improvement in an Axial Compressor by Continuous and Pulsed Tip Injection

open access: yesInternational Journal of Turbomachinery, Propulsion and Power, 2022
Stall and surge are strong limitations in the operating range of compressors and thus one of the major limits of jet engine performance. A promising way to push the stability limit of compression machines is to inject a small amount of flow at the blade ...
Joseph Moubogha Moubogha   +4 more
doaj   +1 more source

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