Results 51 to 60 of about 102,749 (268)
A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
The Astrophysical JournalInternal gas inflows driven by galaxy mergers are considered to enhance star formation rates (SFRs), fuel supermassive black hole growth, and stimulate active galactic nuclei (AGNs).
Kiyoaki Christopher Omori +8 more
doaj +1 more source
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Advanced Science, EarlyView.Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Intensive Broadband Reverberation Mapping of Fairall 9 with 1.8 yr of Daily Swift Monitoring
The Astrophysical JournalWe present 1.8 yr of near-daily Swift monitoring of the bright, strongly variable Type 1 active galactic nucleus (AGN) Fairall 9. Totaling 575 successful visits, this is the largest such campaign reported to date.
R. Edelson +7 more
doaj +1 more source
Combining LOFAR and Apertif Data for Understanding the Life Cycle of Radio Galaxies
Galaxies, 2021 Active galactic nuclei (AGN) at the centres of galaxies can cycle between periods of activity and of quiescence. Characterising the duty-cycle of AGN is crucial for understanding their impact on the evolution of the host galaxy.
Raffaella Morganti +12 more
doaj +1 more source
Chemistry in isolation: High CCH/HCO+ line ratio in the AMIGA galaxy CIG 638
, 2014 Multi-molecule observations towards an increasing variety of galaxies have been showing that the relative molecular abundances are affected by the type of activity.
Aladro, R. +6 more
core +1 more source
A Study of Nine High-Redshift Clusters of Galaxies: IV. Photometry and Sp ectra of Clusters 1324+3011 and 1604+4321 [PDF]
, 2001 New photometric and spectroscopic observations of galaxies in the directions of three distant clusters are presented as part of our on-going high-redshift cluster survey.
Adami C. +15 more
core +2 more sources
Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Radio Sources in the 2dF Galaxy Redshift Survey. I. Radio Source Populations [PDF]
, 1999 We present the first results from a study of the radio continuum properties of galaxies in the 2dF Galaxy Redshift Survey, based on thirty 2dF fields covering a total area of about 100 square degrees.
C. A. Jackson +7 more
core +3 more sources
Advanced Science, EarlyView.The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty +21 more
wiley +1 more source