Results 31 to 40 of about 129,145 (314)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Active ingredients of dandelion and its research progress in animal production and application

Siliao yanjiu, 2021
Chinese herbal medicine feed additives have the advantages of no drug residue, no side effects, low toxicity, and rich nutritional content, and can be used as a substitute for antibiotic drugs.
Yang ZHAO, Na LIU, Yuan WANG, Min SONG, Rui-fang WANG, Yan-ping YANG, Jing-wei QI, Xiao-ping AN   +7 more
doaj  

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Determination of the active ingredient amounts of expired albendazole drugs

Medicine Science
In this study, it was aimed to determine the active ingredient amounts of 24 expired and 3 unexpired antiparasitic drugs containing the active ingredient albendazole using UV-Vis and RP-HPLC techniques. The drugs were prepared using methanol (MeOH) and 1
Nurhayat Atasoy, Funda Aydin, Fatma Akpolat, Ufuk Mercan Yucel   +3 more
doaj   +1 more source

Dünnschichtchromatographische Untersuchungen von Dibenz[b,f]azepinen

CHIMIA, 1969
Thin layer chromatographic purity determination of commercial desipramine hydrochloride (active ingredient of Pertofran®) and clomipramine hydrochloride (active ingredient of Anafranil®) shows the presence of some impurities, the identity and quantity ...
K. Adank, T. Schmidt
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Effects of Traditional Chinese Medicine and its Active Ingredients on Drug-Resistant Bacteria

Frontiers in Pharmacology, 2022
The increasing and widespread application of antibacterial drugs makes antibiotic resistance a prominent and growing concern in clinical practice. The emergence of multidrug-resistant bacteria presents a global threat. However, the development and use of
Jimin Li, Jimin Li, Shanshan Feng, Xin Liu, Xu Jia, Xu Jia, Fengling Qiao, Jinlin Guo, Jinlin Guo, Shanshan Deng, Shanshan Deng   +10 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Decomposition of the Active Ingredient of Pesticides During Storage

Madras Agricultural Journal, 1967
The effect of exposure of pesticides and formulated products to atmospheric conditions, particularly to high summer temperatures is considerable. At Rothamsted, Burt and Ward (1955) have explained the rapid volatalisation of D. D. T.
N. M. THYAGARAJAN and N. S. VENKATARAMAN
doaj   +1 more source