Results 131 to 140 of about 9,047 (257)

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

A Qualitative Exploration of Paid Carers' Experience of Caring for Men With Intellectual and/or Developmental Disability and Harmful Sexual Behaviour. [PDF]

J Appl Res Intellect Disabil
Drew E, Richardson L, Murphy G, Rose J.
europepmc   +1 more source

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Facilitating Research Participation: How Researchers Support People With Communication Support Needs to Decide to Participate. [PDF]

J Appl Res Intellect Disabil
Lutz DL, Fisher KR.
europepmc   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

(En)Abling Architectural Research: Co-Designing With People With Intellectual Disabilities. [PDF]

J Appl Res Intellect Disabil
Kasem M, Kaleem Z, Clark S, Sakellariou D.   +3 more
europepmc   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, EarlyView.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source

Relationship between pain, quality of sleep, sleep bruxism and patients' personality among individuals with reported orofacial pain. [PDF]

Sci Rep
Orzeszek S, Martynowicz H, Smardz J, Wojakowska A, Bombała W, Jenca A, Więckiewicz M.   +6 more
europepmc   +1 more source

Self‐Sustaining Hybrid Passive Cooler Enabling Highly Effective Thermal Management for Outdoor Electronics

Advanced Science, EarlyView.
An innovative hybrid passive cooler integrates a porous radiative coating and an atmospheric moisture‐harvesting hydrogel within a melamine sponge skeleton, synergizing radiative cooling, sensible‐heat absorption, and latent‐heat evaporation. It maintains an average 8.3°C sub‐ambient cooling under sunlight and a maximum ∼42.4°C drop under 2000 W·m−2 ...
Qingyuan Du, Meng Yang, Maoning Li, Guangzhe Chen, Yunpeng Hu, Dandan Li, Dazhi Sun   +6 more
wiley   +1 more source

Balancing in Virtual Reality: Motor Learning and Functional Improvement in Down Syndrome. [PDF]

J Intellect Disabil Res
Ardai E, Vámos T, Papp G, Berencsi A.
europepmc   +1 more source