Results 131 to 140 of about 3,376,565 (288)
İBN SİNA'DA BEDENSİZ KALAN RUHLARIN FERDİYETLERİNİN KORUNUP KORUNMADIĞINA DAİR PROBLEM ÜZERİNE
Felsefe Dünyası, 2009 İBN SİNA'DA BEDENSİZ KALAN RUHLARIN FERDİYETLERİNİN KORUNUP KORUNMADIĞINA DAİR PROBLEM ...
Eyüp Şahin
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Advanced Science, EarlyView.This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source
Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo
Advanced Science, EarlyView.As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao +12 more
wiley +1 more source
Advanced Science, EarlyView.In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang +11 more
wiley +1 more source
Avicenna on the Reality of Prophetic Revelation and Its Comparison with Quranic Doctrines
حکمت سینوی, 2018 According to the Quranic teachings, prophetic revelation is the Word of God that is revealed to the prophets upon the prophets based on the special choice of the Lord.
Zahra Mahmoud Kelayeh
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Advanced Science, EarlyView.Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu +11 more
wiley +1 more source
TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains
Advanced Science, EarlyView.Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang +14 more
wiley +1 more source
Michael Frede's "The Aristotelian Theory of the Agent Intellect" [translation]
This is a rough translation of Michael Frede's "La théorie aristotélicienne de l'intellect agent" published in 1996. This insightful paper contains an important interpretation of Aristotle's notoriously difficult theory of the active intellect from De ...
Murray, Samuel
core +3 more sources
Advanced Science, EarlyView.In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang +8 more
wiley +1 more source
Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2018 Aproape în fiecare zi, omul este afectat de diferite tipuri de factori de stres și de necesitatea de a găsi soluții optime în varietatea de situații de viața.
Igori DONCENCO, Ludmila ANŢIBOR
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