Results 91 to 100 of about 11,928,939 (371)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Active Learning through Materials Development: A Project for the Advanced L2 Classroom [PDF]

open access: yesJournal of the National Council of Less Commonly Taught Languages, 2008
Building on the notion of active learning, the assumption that students learn more when given opportunities to practice using their skills and to receive feedback on their performance, this article de-scribes a project undertaken in an Advanced (third ...
Katrina Daly Thompson
doaj  

Human-Like Active Learning: Machines Simulating the Human Learning Process [PDF]

open access: yesarXiv, 2020
Although the use of active learning to increase learners' engagement has recently been introduced in a variety of methods, empirical experiments are lacking. In this study, we attempted to align two experiments in order to (1) make a hypothesis for machine and (2) empirically confirm the effect of active learning on learning.
arxiv  

Active Discriminative Text Representation Learning

open access: yes, 2016
We propose a new active learning (AL) method for text classification with convolutional neural networks (CNNs). In AL, one selects the instances to be manually labeled with the aim of maximizing model performance with minimal effort.
Lease, Matthew   +2 more
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Current teachers’ perceptions and students' perspectives regarding activities modalities, instructional settings during primary school physical education classes in China: a cross-sectional observational study

open access: yesFrontiers in Sports and Active Living
IntroductionThis study set out to understand the association between teaching practices, teacher confidence, competence, self-efficacy, and the resulting student outcomes.MethodsData regarding teaching behaviours were collected via video recording and ...
Jin Yan   +10 more
doaj   +1 more source

Combining active learning suggestions [PDF]

open access: yesPeerJ Computer Science, 2018
We study the problem of combining active learning suggestions to identify informative training examples by empirically comparing methods on benchmark datasets. Many active learning heuristics for classification problems have been proposed to help us pick
Alasdair Tran   +2 more
doaj   +2 more sources

Active Learning Augmented Reality for STEAM Education—A Case Study

open access: yes, 2020
Immersive technologies are rapidly transforming the field of education. Amongst them, Augmented Reality (AR) has shown promise as a resource, particularly for education in Science, Technology, Engineering, Arts, and Mathematics (STEAM).
J. Jesionkowska, Fridolin Wild, Y. Deval
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

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