Results 171 to 180 of about 540,685 (254)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Self-sustained frictional cooling in active matter. [PDF]

Nat Commun
Antonov AP, Musacchio M, Löwen H, Caprini L.   +3 more
europepmc   +1 more source

Computer modeling reveals modalities to actuate mutable, active matter. [PDF]

Nat Commun, 2022
Laskar A, Manna RK, Shklyaev OE, Balazs AC.   +3 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Metareview: a survey of active matter reviews. [PDF]

Eur Phys J E Soft Matter
Te Vrugt M, Wittkowski R.
europepmc   +1 more source

Collective pattern formations of animals in active matter physics. [PDF]

Biophys Physicobiol, 2021
Sugi T, Ito H, H Nagai K.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The 2025 motile active matter roadmap. [PDF]

J Phys Condens Matter
Gompper G, Stone HA, Kurzthaler C, Saintillan D, Peruani F, Fedosov DA, Auth T, Cottin-Bizonne C, Ybert C, Clément E, Darnige T, Lindner A, Goldstein RE, Liebchen B, Binysh J, Souslov A, Isa L, di Leonardo R, Frangipane G, Gu H, Nelson BJ, Brauns F, Marchetti MC, Cichos F, Heuthe VL, Bechinger C, Korman A, Feinerman O, Cavagna A, Giardina I, Jeckel H, Drescher K.   +31 more
europepmc   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Programmed mechano-chemical coupling in reaction-diffusion active matter. [PDF]

Sci Adv, 2021
Senoussi A, Galas JC, Estevez-Torres A.
europepmc   +1 more source