Results 81 to 90 of about 540,685 (254)

Anisotropic mesoscale turbulence and pattern formation in microswimmer suspensions induced by orienting external fields

open access: yesNew Journal of Physics, 2019
This paper studies the influence of orienting external fields on pattern formation, particularly mesoscale turbulence, in microswimmer suspensions. To this end, we apply a hydrodynamic theory that can be derived from a microscopic microswimmer model ...
Henning Reinken   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Incompressible polar active fluids in the moving phase in dimensions d > 2

open access: yesNew Journal of Physics, 2018
We study universal behavior in the moving (polar ordered) phase of a generic system of motile particles with alignment interactions in the incompressible limit for spatial dimensions d  > 2. Using a dynamical renormalization group analysis, we obtain the
Leiming Chen, Chiu Fan Lee, John Toner
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Active dynamics of tissue shear flow

open access: yesNew Journal of Physics, 2017
We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells as well as a contribution to overall tissue shear flow due to ...
Marko Popović   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Confined active Brownian particles: theoretical description of propulsion-induced accumulation

open access: yesNew Journal of Physics, 2018
The stationary-state distribution function of confined active Brownian particles (ABPs) is analyzed by computer simulations and analytical calculations. We consider a radial harmonic as well as an anharmonic confinement potential. In the simulations, the
Shibananda Das   +2 more
doaj   +1 more source

Dynamics of self-propelled particles passing a bottleneck

open access: yesNew Journal of Physics, 2020
We study the passage of active and passive granular particles through a bottleneck under gravitational bias. The grains are pharmaceutical capsules with spherocylindrical shapes on a vibrating table. The vibrating ground plate is slightly tilted in order
Mahdieh Mohammadi   +5 more
doaj   +1 more source

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