Results 21 to 30 of about 13,744,820 (237)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysis of different methods of suppressing generator noise reaching indoor noise
European Mechanical Science, 2022 The noise which occurs during the operation of the auxiliary power units is a disturbing factor, although its level varies depending on the environment.
Filiz Bal Koçyiğit +2 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Internal Model Control for a Light-Weight Active Noise-Reducing Casing
Archives of Acoustics, 2016 The active noise-reducing casing developed and promoted by the authors in recent publications have multiple advantages over other active noise control methods.
Krzysztof MAZUR, Marek PAWEŁCZYK
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Investigations on drone-mounted active noise control
Acta AcusticaAlthough drones have many potential applications including parcel delivery and surveillance, their deployment in urban areas is limited by their noise levels.
Steiner Jonas +2 more
doaj +1 more source
International Journal of Environmental Health Engineering, 2015 Aims: The main goal of this paper was to evaluate the effectiveness of Helmholtz resonator in noise reduction of duct equipped with active noise control (ANC). Materials and Methods: Noise frequency band was produced by a propeller fan, which was spread
Farhad Forouharmajd +3 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Noise mitigation with active acoustic metamaterials
Acta AcusticaThe potential of active metamaterials to address long-standing challenges such as noise mitigation has been recognized for several decades. However, the research of active structures capable to meet these challenges has been slow due to issues such as ...
Kovacevich Dylan A. +5 more
doaj +1 more source