Results 61 to 70 of about 10,851,693 (251)

A simple active damping method for Active Power Filters

, 2016
Active Power Filters (APFs) are widely applied devices in the power quality field for control flexibility and effective attenuation of the harmonic, reactive and negative components of the grid current and voltage. As the interface connecting an APF with
Xinjian Jiang, Huawei Yuan, Yuan, Huawei, Jiang, Xinjian   +3 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Multi-Objective Optimal Location of Distributed Generators & Capacitor Banks into Radial Distribution Network by Novel Metaheuristic Optimisation

Energies
The integration of renewable-based distributed units into distributed systems has been aided by recently developed technologies based on renewable energy, changes to utility infrastructure, and progressive government regulations.
Shilpa Phatak, Lakhan S. Titare, Arvind Sharma, Nitin Saxena   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Control of 3-level shunt active power filter using harmonic selective controller [PDF]

, 2006
In this paper the control of 3-level shunt active power filter is proposed using frequency selective proportional plus multiple resonant controllers. The voltage source converter (VSC) is operated using ramp-comparison current control method.
A. Joshi, R. Gupta, Ghosh, Arindam, Gupta, Rajesh, Joshi, Avinash, A. Ghosh   +5 more
core   +2 more sources

Effect of distributed generation placement to load noise on the KH-01 feeder at PT. PLN (PERSERO) ULP Krueng Geukueh

Journal Geuthee of Engineering and Energy
Distributed Generation is a power plant with a small capacity which is usually located close to the load in the electric power distribution system. One effort to reduce the value of power losses and also improve voltage drops in the distribution network ...
Muhammad Azizi, Selamat Meliala
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source