Results 21 to 30 of about 8,677,870 (233)

Influence of Ambient Pressure on the Jet-Ignition Combustion Performance and Flame Propagation Characteristics of Gasoline in a Constant Volume Combustion Chamber

Energies
Based on a constant volume combustion chamber, the initial ambient pressure effect on gasoline combustion performance and flame propagation of the active and passive pre-chamber ignition systems were studied.
Zongjie Hu, Minglong Li, Xinke Miao, Zhiyu Wang, Yuanzhi Tang, Xijiang Wu, Wangchao Yu, Zhe Kang, Jun Deng   +8 more
doaj   +1 more source

Study on combustion and emissions of methanol engines based on active pre-chamber jet ignition technology

Case Studies in Thermal Engineering
Against the backdrop of the ''dual carbon'' goals, this study addressed the challenges of narrow lean-burn limits and low thermal efficiency in conventional spark-ignition (SI) methanol engines by proposing the active pre-chamber jet ignition (APCH-JI ...
Yafeng Ren, Hong Jia, Jiaxin Qin, Qisheng Zhang, Jinyan Du   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Correlations between fuel properties and combustion inside an active pre-chamber

Applications in Energy and Combustion Science
An active pre-chamber (PC) in a spark-ignition engine is a promising approach to extend the lean operating limit, thereby, increasing the indicated efficiency.
Patrick Burkardt, Sanket Girhe, Bastian Lehrheuer, Heinz Pitsch, Stefan Pischinger   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Lean ammonia-fueled engine operation enabled by hydrogen-assisted turbulent jet ignition

Frontiers in Mechanical Engineering
Anhydrous ammonia (NH3) use in internal combustion engines represents a zero-carbon energy solution that is fully sustainable if NH3 is generated renewably.
Shawn A. Reggeti, William F. Northrop
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

CFD Simulation of Pre-Chamber Spark-Ignition Large Bore CNG Engine: Model Development, Practical Applications, and Experimental Validation

Energies
This study develops and validates a three-dimensional CFD model for a 12 L large-bore active-type pre-chamber spark-ignition (PCSI) engine fueled by natural gas.
Soo-Jin Jeong, Seokpan Seo, Seong-Joon Moon   +2 more
doaj   +1 more source

Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice. [PDF]

PLoS ONE, 2018
The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study, B16-F10 cells are used to develop a primary tumor model by implanting them directly into the ...
Marine Potez, Verdiana Trappetti, Audrey Bouchet, Cristian Fernandez-Palomo, Esra Güç, Witold W Kilarski, Ruslan Hlushchuk, Jean Laissue, Valentin Djonov   +8 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source