Results 31 to 40 of about 8,677,870 (233)

Detection of Subclinical Left Ventricular Dysfunction in Active Rheumatoid Arthritis during Biological Treatment by Two- Dimensional Speckle Tracking Echocardiography [PDF]

Al-Azhar International Medical Journal
Background: One crucial element in the progression of rheumatoid arthritis (RA) is the cytokine tumor necrosis factor-α (TNF-α).Objectives: To compare the pre- and post-biological treatment left ventricular (LV) systolic performance in a group of ...
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Controllability of Pre-Chamber Induced Homogeneous Charge Compression Ignition and Performance Comparison with Pre-Chamber Spark Ignition and Homogeneous Charge Compression Ignition

Applied Sciences
This paper presents an experimental and numerical evaluation of the pre-chamber induced HCCI combustion concept (PC-HCCI) in terms of engine performance, emissions, and controllability.
Josip Krajnović, Sara Ugrinić, Viktor Dilber, Darko Kozarac   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Recent advances with a hybrid micro-pattern gas detector operated in low pressure H2 and He, for AT-TPC applications

EPJ Web of Conferences, 2018
In view of a possible application as a charge-particle track readout for an Active-Target Time Projection Chamber (AT-TPC), the operational properties and performances of a hybrid Micro-Pattern Gaseous Detector (MPGD) were investigated in pure low ...
Cortesi Marco, Mittig Wolfgang, Bazin Daniel, Limonge Yassid Ayyad, Beceiro-Novo Saul, Tanani Rim Soussi, Wolff Michael, Yurkon John, Stolz Andreas   +8 more
doaj   +1 more source

A novel clinical sign in intraocular tuberculosis: Active chorioretinitis within chorioretinal atrophy

American Journal of Ophthalmology Case Reports, 2017
Purpose: To report a novel clinical sign in patients with intraocular tuberculosis. The current study is an observational consecutive case series of patients diagnosed with intraocular tuberculosis managed at a tertiary eye care centre from June 1, 2012 ...
Avinash Pathengay, Bhavik Panchal, Himadri Choudhury, Soumyava Basu, Nidhi Relhan, Harry W. Flynn, Jr.   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Students’ Satisfaction with Hybrid Learningin the School of Accountancy, Universityof the Thai Chamber of Commerce:A Case Study of Principles of Accounting

, 2011
The primary objective of this research was to study student’s satisfactory levels withhybrid learning, School of Accountancy, University of the Thai Chamber of Commerce:A Case Study of Principles of Accounting.
Chowivattana, Isaree
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Experimental investigation on the effect of compression ratio on detonation combustion characteristics of active pre-chamber engine

Case Studies in Thermal Engineering
Turbulent Jet Ignition (TJI) engines show promising potential for enhancing engine efficiency. However, they differ significantly from conventional spark ignition engines in terms of in-cylinder combustion modes, rendering traditional detonation ...
Jingxun Yang, Fangxi Xie, Xiaoping Li, Beiping Jiang, Zhaohui Jin, Bo shen, Yu Liu   +6 more
doaj   +1 more source