Results 161 to 170 of about 10,165,445 (355)

A Quadruple Magnetic Source Model for Arcade Flares and X-Ray Arcade Formations outside Active Regions I. Dark Filament Suspension and the Magnetic Structure in the Pre-Event Regions [PDF]

, 1999
Yutaka Uchida, Shigenobu Hirose, Samuel Cable, Satoshi Morita, M. Torii, Shuhei Uemura, Tomotaka Yamaguchi   +6 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

First Insights into the Applicability and Importance of Different 3D Magnetic Field Extrapolation Approaches for Studying the Preeruptive Conditions of Solar Active Regions

The Astrophysical Journal
The three-dimensional (3D) coronal magnetic field has not yet been directly observed. However, for a better understanding and prediction of magnetically driven solar eruptions, 3D models of solar active regions are required.
Marianna B. Korsós, Robert Jarolim, Robertus Erdélyi, Astrid M. Veronig, Huw Morgan, Francesca Zuccarello   +5 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Identifying Active Aging Policy Objectives in Italian Regions

Social Sciences
Background: In light of the main challenges recognized as being linked to the operationalization of the active aging concept at the policy level, the present study aimed to understand whether and to what extent Italian regional governments plan to deal ...
Davide Lucantoni, Giovanni Lamura, Marco Socci, Francesco Barbabella, Valerio Intraligi, Andrea Principi   +5 more
doaj   +1 more source

Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid Cells. [PDF]

J Virol, 2020
Wang L, Laing J, Yan B, Zhou H, Ke L, Wang C, Narita Y, Zhang Z, Olson MR, Afzali B, Zhao B, Kazemian M.   +11 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

ATM-Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions. [PDF]

Adv Sci (Weinh), 2020
Hu K, Li Y, Wu W, Xie L, Yan H, Cai Y, Chen D, Jiang Q, Lin L, Chen Z, Liao JY, Zhang Y, Koeffler HP, Yin D, Yin D, Song E.   +15 more
europepmc   +1 more source

Super active regions and production of major solar flares [PDF]

The success of imaging detectors with small fields of veiw such as HXIS or P/OF (Pinhole/Occulter Facility) depends heavily on pointing to the right place at the right time.
Bai, T.
core   +1 more source