Results 191 to 200 of about 1,351,620 (240)

Simultaneous tDCS-fMRI reveals limited and inconsistent changes in functional connectivity: Insights from a temporal dynamics study. [PDF]

Imaging Neurosci (Camb)
Klooster DCW, Wu GR, de Witte S, Kaalberg K, Kalkhoven B, Mestrom RMC, Baeken C.   +6 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Dictionary Learning Methods for Brain Activity Mapping with MEG Data. [PDF]

Brain Topogr
Calvetti D, Somersalo E.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Nuclear speckles: a fundamental layer of gene regulation. [PDF]

Trends Cell Biol
Namba H, Mir S, Groce EL, Alexander KA.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Scalable Bayesian Image-on-Scalar Regression for Population-Scale Neuroimaging Data Analysis. [PDF]

J Am Stat Assoc
Xu Y, Johnson TD, Nichols TE, Kang J.
europepmc   +1 more source

Anatomically constrained volumetric smoothing enhances fMRI reliability while avoiding smoothing artifacts. [PDF]

Front Neuroimaging
Ellis DG, Aizenberg MR.
europepmc   +1 more source

Mapping Functionally Relevant Tractable Lysines of Challenging Protein Targets by Covalent Fragment Screening. [PDF]

Chembiochem
Csorba N, Ábrányi-Balogh P, Orgován Z, Szalai TV, Ferenczy GG, Kollár L, Péczka N, Imre T, Simon J, Szabó P, Schlosser G, Hrast M, Gobec S, Ivanova V, Galdeano C, Kopranovic A, Neumann M, Meyer-Almes FJ, Keserű GM.   +18 more
europepmc   +1 more source