Results 141 to 150 of about 376,531 (312)
'Doing it already'?: stakeholder perceptions of Housing First in the UK
, 2012 When first developed in the United States, ‘Housing First’ was highly controversial given its departure from mainstream ‘linear’ service models for homeless people with complex support needs.
Johnsen, Sarah, Teixeira, Ligia
core +1 more source
The Quality and Bioactive Properties of Mulberry Wine Under Different Fermentation Conditions
FoodsThis study systematically investigated the effects of key fermentation parameters—initial sugar content (24–28 °Brix), temperature (15–20 °C), and yeast inoculation rate (0.04–0.12%)—on the quality, volatile aroma characteristics, antioxidant capacity ...
Jiajun Li, Huiming Zhang, Tieyan Jin
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
, 2014 Recent findings indicate that South Africa and, in particular, the Western Cape has some of the highest prevalence of substance use disorders and substance related problems in the world.
Hazell, Nic
core
, 2018 The most popular methods of organochlorinated pesticides (OCP) destruction, which are based on thermal dechlorination, are not ecologically safe. The other process – radiation-chemical degradation – has got some advantages.
A. Oudalova +11 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A Theology of Lament from the Psalms through the Lens of Active Substance Addiction
, 2018 This thesis develops a theology of lament through the lens of active substance addiction by engaging with the individual lament Psalms. As the psalmist shows there to be a relationship between his/her sin and the subsequent negative situation in the ...
Dyck, Andrew William
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source