Results 121 to 130 of about 427,344 (311)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Motion sickness and tilts of the inertial force environment: active suspension systems vs. active passengers

, 2003
Background: Maneuvering in vehicles exposes occupants to low frequency forces (
Bles, W., Golding, J.F., Gresty, M.A., Bos, E., Haynes, T.   +4 more
core  

Reconstructing the feeding ecology of Cambrian sponge reefs: the case for active suspension feeding in Archaeocyatha. [PDF]

R Soc Open Sci, 2023
Gibson BM, Chipman M, Attanasio P, Qureshi Z, Darroch SAF, Rahman IA, Laflamme M.   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Reduction of bridge dynamic amplification through adjustment of vehicle suspension damping

, 2007
This paper presents a novel approach to the reduction of short-span bridge dynamic responses to heavy vehicle crossing events. The reductions are achieved through adjustment of the vehicle suspension damping coefficient just before the crossing.
O\u27Brien, Eugene J., Harris, Niall K., O'Brien, Eugene J., González, Arturo   +3 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Active force control on active suspension system [PDF]

, 2013
Active force control system is the most effective and robust system in surpass vibration on suspension system. The objective of this project is to study the performance of AFC on car suspension system.
Mohd Salehuddin, Idres
core  

Research on Deep Reinforcement Learning Control Algorithm for Active Suspension Considering Uncertain Time Delay. [PDF]

Sensors (Basel), 2023
Wang Y, Wang C, Zhao S, Guo K.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Mathematical Modeling of Suspension Systems

Mathematical modeling of vehicle suspensions is essential in understanding and optimizing their performance characteristics. The development of mathematical models for vehicle suspensions involves capturing the dynamic interactions between suspension ...
Sun, Chen, Khajepour, Amir, Lu, Yukun
core   +1 more source