Background/Aims: The Xi-Huang (XH) formula has been used for breast cancer treatment in traditional Chinese medicine (TCM) since 1740. In this study, we show that, XH extract could suppress the growth of breast cancer cells in vitro and in vivo, and that
Jian Hao+9 more
doaj +1 more source
Ultrastructural Analysis of the Digestive Gland Secretory and Absorptive Processes in Nepenthes glandulifera [PDF]
Nepenthes glandulifera is a carnivorous pitcher plant native to tropical environments, of which the majority live on the islands in the Malay Archipelago where sunlight and water are abundant.
Manuel, Shannon
core +1 more source
Identification and functional analysis of NOL7 nuclear and nucleolar localization signals
Background NOL7 is a candidate tumor suppressor that localizes to a chromosomal region 6p23. This locus is frequently lost in a number of malignancies, and consistent loss of NOL7 through loss of heterozygosity and decreased mRNA and protein expression ...
Lingen Mark W+2 more
doaj +1 more source
Evolution of plant reproduction: from fusion and dispersal to interaction and communication [PDF]
Based on the existing data concerning the evolution of the sexual reproduction, it is argued that the processes of sex differentiation and interactions play a key role in evolution. From the beginning environment and organism are unified.
Willemse, M.T.M.
core +1 more source
Modeling Regulation of Zinc Uptake via ZIP Transporters in Yeast and Plant Roots [PDF]
In yeast (Saccharomyces cerevisiae) and plant roots (Arabidopsis thaliana) zinc enters the cells via influx transporters of the ZIP family. Since zinc is both essential for cell function and toxic at high concentrations, tight regulation is essential for cell viability.
arxiv +1 more source
Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels [PDF]
In the metazoan replication timing program, clusters of replication origins located in different subchromosomal domains fire at different times during S phase. We have used Xenopus laevis egg extracts to drive an accelerated replication timing program in
Alexander M. Thomson+64 more
core +4 more sources
Long-distance retinoid signaling in the zebra finch brain. [PDF]
All-trans retinoic acid (ATRA), the main active metabolite of vitamin A, is a powerful signaling molecule that regulates large-scale morphogenetic processes during vertebrate embryonic development, but is also involved post-natally in regulating neural ...
Tina C Roeske+4 more
doaj +1 more source
Engineering intracellular active transport systems as in vivo biomolecular tools.
Active transport systems provide essential functions in terms of cell physiology and metastasis. These systems, however, are also co-opted by invading viruses, enabling directed transport of the virus to and from the cell's nucleus (i.e., the site of ...
G. Bachand, A. Carroll-Portillo
semanticscholar +1 more source
The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]
In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
core +1 more source
Acid-Labile Traceless Click Linker for Protein Transduction [PDF]
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M.+21 more
core +1 more source