Results 91 to 100 of about 610,101 (198)

Antiestrogenic Activity of the Xi-Huang Formula for Breast Cancer by Targeting the Estrogen Receptor α

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: The Xi-Huang (XH) formula has been used for breast cancer treatment in traditional Chinese medicine (TCM) since 1740. In this study, we show that, XH extract could suppress the growth of breast cancer cells in vitro and in vivo, and that
Jian Hao   +9 more
doaj   +1 more source

Ultrastructural Analysis of the Digestive Gland Secretory and Absorptive Processes in Nepenthes glandulifera [PDF]

open access: yes, 2019
Nepenthes glandulifera is a carnivorous pitcher plant native to tropical environments, of which the majority live on the islands in the Malay Archipelago where sunlight and water are abundant.
Manuel, Shannon
core   +1 more source

Identification and functional analysis of NOL7 nuclear and nucleolar localization signals

open access: yesBMC Cell Biology, 2010
Background NOL7 is a candidate tumor suppressor that localizes to a chromosomal region 6p23. This locus is frequently lost in a number of malignancies, and consistent loss of NOL7 through loss of heterozygosity and decreased mRNA and protein expression ...
Lingen Mark W   +2 more
doaj   +1 more source

Evolution of plant reproduction: from fusion and dispersal to interaction and communication [PDF]

open access: yes, 2009
Based on the existing data concerning the evolution of the sexual reproduction, it is argued that the processes of sex differentiation and interactions play a key role in evolution. From the beginning environment and organism are unified.
Willemse, M.T.M.
core   +1 more source

Modeling Regulation of Zinc Uptake via ZIP Transporters in Yeast and Plant Roots [PDF]

open access: yes, 2012
In yeast (Saccharomyces cerevisiae) and plant roots (Arabidopsis thaliana) zinc enters the cells via influx transporters of the ZIP family. Since zinc is both essential for cell function and toxic at high concentrations, tight regulation is essential for cell viability.
arxiv   +1 more source

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels [PDF]

open access: yes, 2010
In the metazoan replication timing program, clusters of replication origins located in different subchromosomal domains fire at different times during S phase. We have used Xenopus laevis egg extracts to drive an accelerated replication timing program in
Alexander M. Thomson   +64 more
core   +4 more sources

Long-distance retinoid signaling in the zebra finch brain. [PDF]

open access: yesPLoS ONE, 2014
All-trans retinoic acid (ATRA), the main active metabolite of vitamin A, is a powerful signaling molecule that regulates large-scale morphogenetic processes during vertebrate embryonic development, but is also involved post-natally in regulating neural ...
Tina C Roeske   +4 more
doaj   +1 more source

Engineering intracellular active transport systems as in vivo biomolecular tools.

open access: yes, 2006
Active transport systems provide essential functions in terms of cell physiology and metastasis. These systems, however, are also co-opted by invading viruses, enabling directed transport of the virus to and from the cell's nucleus (i.e., the site of ...
G. Bachand, A. Carroll-Portillo
semanticscholar   +1 more source

The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]

open access: yes, 1988
In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
core   +1 more source

Acid-Labile Traceless Click Linker for Protein Transduction [PDF]

open access: yes, 2012
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M.   +21 more
core   +1 more source

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