Results 121 to 130 of about 610,101 (198)
Mathematical model of Nucleocytoplasmic Transport and Nuclear-to-Cell Ratio in a growing cell [PDF]
arXivIt has been observed that the growth of the nucleus and the cytoplasm is coordinated during cell growth, resulting in a nearly constant nuclear-to-cell volume ratio (N/C) throughout the cell cycle. Previous studies have shown that the N/C ratio is determined by the ratio between the number of proteins in the nucleus and the total number of proteins in ...
arxiv
Mechanical oscillations at the cellular scale [PDF]
arXiv, 2001 Active phenomena which involve force generation and motion play a key role in a number of phenomena in living cells such as cell motility, muscle contraction and the active transport of material and organelles. Here we discuss mechanical oscillations generated by active systems in cells. Examples are oscillatory regimes in muscles, the periodic beating
arxiv
Emergent properties of the G1/S network [PDF]
, 2010 Tato práce se zabývá buněčným cyklem kvasinky Saccgaromyces cerevisiae. Oblastí našeho zájmu je přechod mezi G1 a S fází, kde je naším cílem identifikovat velikosti buňky v době počátku DNA replikace.
Dražková, Jana
core
Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia [PDF]
Oncotarget, Impact journals, 2018, 2019 Background: Chronic myeloid leukemia (CML) results from hematopoietic stem cell transformation by the bcr-abl chimeric oncogene, encoding a 210 kDa protein with constitutive tyrosine kinase activity. In spite of the efficiency of tyrosine kinase inhibitors (TKI; Imatinib), other strategies are explored to eliminate CML leukemia stem cells, such as ...
arxiv
International Journal of Nanomedicine, 2012 Min Guan1, Qiao-Ling Zhu1, Yang Liu1, Yong-Yan Bei1, Zong-Lin Gu1, Xue-Nong Zhang1, Qiang Zhang21Department of Pharmaceutics, College of Pharmaceutical Science, Soochow University, Suzhou, People's Republic of China; 2Department of Pharmaceutics,
Zhang Q +6 more
doaj
Codominance and toxins: A path to drugs of nearly unlimited selectivity [PDF]
, 1995 The effectiveness of drugs is often limited by their insufficient selectivity. I propose designs of therapeutic agents that address this problem. The key feature of these reagents, termed comtoxins (codominance-mediated toxins), is their ability to ...
Varshavsky, Alexander
core
Carbon turnover in the water-soluble protein of the adult human lens. [PDF]
, 2013 PurposeHuman eye lenses contain cells that persist from embryonic development. These unique, highly specialized fiber cells located at the core (nucleus) of the lens undergo pseudo-apoptosis to become devoid of cell nuclei and most organelles. Ostensibly
Buchholz, Bruce A +7 more
core +1 more source
Principles Of Differentiation And Morphogenesis [PDF]
, 2016 Developmental biology is the science connecting genetics with anatomy, making sense out of both. The body builds itself from the instructions of the inherited DNA and the cytoplasmic system that interprets the DNA into genes and creates intracellular and
Gilbert, Scott F., Rice, R.
core +1 more source
Drug Design, Development and Therapy, 2017 Tatiana A Slastnikova,1 Andrey A Rosenkranz,1,2 Yuri V Khramtsov,1 Tatiana S Karyagina,1 Sergey A Ovechko,2 Alexander S Sobolev1,2 1Laboratory of Molecular Genetics of Intracellular Transport, Institute of Gene Biology, Russian Academy of Sciences ...
Slastnikova TA +5 more
doaj
Ludwig-Soret microscopy with vibrational photothermal effect [PDF]
arXivVibrational microscopy provides label-free, bond-selective chemical contrast by detecting molecular vibrations, making it invaluable for biomedical research. While conventional methods rely on the direct detection of Raman scattering or infrared absorption, recently developed vibrational photothermal (ViP) microscopy achieves chemical contrast ...
arxiv