Results 141 to 150 of about 6,158,462 (316)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Note from Social and Entertainment, Community Activities, Heart Mountain, April 13, 1944

open access: yes, 1944
Schedule of recreational activities at Heart Mountain incarceration camp. Includes Youth Organizations, Adult Activities, Cubs and Brownies, and Churches.The Japanese American Archival Collection documents the people, places, and daily life of Japanese ...
Community Activities Section
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Student Unions and Activities Board of Governors Minutes, 2012-2013

open access: yes, 2013
These minutes were scanned from bound volumes. Physical copies of these minutes are kept in the University of Minnesota Archives, and can be requested by contacting the University Archives directly.Student Unions and Activities Board of Governors. (2013).
Student Unions and Activities Board of Governors
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Student Unions and Activities Board of Governors Minutes, 2010-2011

open access: yes, 2011
These minutes were scanned from bound volumes. Physical copies of these minutes are kept in the University of Minnesota Archives, and can be requested by contacting the University Archives directly.Student Unions and Activities Board of Governors. (2011).
Student Unions and Activities Board of Governors
core  

Ovary transplantation: to activate or not to activate [PDF]

open access: yesHuman Reproduction, 2015
Kazuhiro, Kawamura   +7 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Student Unions and Activities Board of Governors Minutes, 2013-2014

open access: yes, 2014
These minutes were scanned from bound volumes. Physical copies of these minutes are kept in the University of Minnesota Archives, and can be requested by contacting the University Archives directly.Student Unions and Activities Board of Governors. (2014).
Student Unions and Activities Board of Governors
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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