Results 141 to 150 of about 7,818,688 (294)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Safety of Multiple Sclerosis Treatments During Pregnancy: An Overview of the EU Regulatory Approach to Risk Management Planning. [PDF]

Pharmacoepidemiol Drug Saf
Strassmann V, Gault N, Stark AK, Vaillant T, Berbain T, Martirosyan L, Sarinic VM, Nordeng HME.   +7 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

How Is Registered Nursing Time Used? A Multicentre Observational Study of Nursing Activities, Scope of Practice, and Opportunities for Workforce Redesign in Medical-Surgical Wards in Italy. [PDF]

Nurs Rep
Ivziku D, Vollero L, Alciati V, Ferramosca FMP, Cotichini V, Reato F, Lommi M, Tartaglini D.   +7 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

'I'm Stronger and Healthier. Yeah, and More Fit' Young Strong and Deadly Program Process Evaluation. [PDF]

Health Promot J Austr
Fraser A, D'Urso T, Biles B, Kerrigan P, Warren L, Macniven R, Fletcher-Lartey S.   +6 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Shaping Development Through Parents: A Scalable Approach to Early Learning. [PDF]

Dev Sci
Nayeli GG, Eugenia NC, Fiona T, Roxana S, Claudia V, Alexandra H.   +5 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Finding Aid for Student Activities Office General Files, 1971-1991

, 1971
The Student Activities Office provides a variety of events, activities, and services aimed at enhancing the out-of-class experiences of UW - Stout students.
Student Activities Office
core