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The Evolution of Nanopore Sequencing [PDF]

Frontiers in Genetics, 2015
The $1,000 Genome project has been drawing increasing attention since its launch a decade ago. Nanopore sequencing, the third-generation, is believed to be one of the most promising sequencing technologies to reach four gold standards set for the $1,000 ...
Yue eWang, Qiuping eYang, Zhimin eWang
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Following the central dogma: Nanopore sequencing from DNA and RNA to proteins [PDF]

iScience
Summary: The first nanopore-based sequencer was launched in 2014, and subsequently, nanopore played an irreplaceable role in disclosing the first complete, gapless sequence of a human genome in 2022 due to its megabase-scale read lengths.
Yutong Wang, Qian Han, Yilong He, Shumin Deng, Ziwei Huang, Ziyan Zhang, Shuaijian Dai, Zhuxin Dong   +7 more
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Nanopore sequencing technology and its applications

MedComm, 2023
Since the development of Sanger sequencing in 1977, sequencing technology has played a pivotal role in molecular biology research by enabling the interpretation of biological genetic codes.
Peijie Zheng, Chuntao Zhou, Yuemin Ding, Bin Liu, Liuyi Lu, Feng Zhu, Shiwei Duan   +6 more
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Nanopore sequencing in microgravity [PDF]

npj Microgravity, 2016
Abstract Rapid DNA sequencing and analysis has been a long-sought goal in remote research and point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological research and close monitoring of crew health, but spaceflight places stringent restrictions on the mass and volume of ...
Alexa B R McIntyre, Lindsay Rizzardi, Angela M Yu, Noah Alexander, Gail L Rosen, Douglas J Botkin, Sarah E Stahl, Kristen K John, Sarah L Castro-Wallace, Ken McGrath, Aaron S Burton, Andrew P Feinberg, Christopher E Mason   +12 more
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Utility of nanopore sequencing for detecting pathogens in bronchoalveolar lavage fluid from pediatric patients with respiratory failure

Journal of Clinical Virology Plus, 2023
RNA viruses are the most frequent pathogens responsible for respiratory infections, particularly in pediatric patients. Next-generation sequencing, represented by Illumina sequencing, is one of the most comprehensive methods for identifying pathogens ...
Makoto Yamaguchi, Kazuhiro Horiba, Kazunori Haruta, Suguru Takeuchi, Takako Suzuki, Yuka Torii, Shinji Kawabe, Sho Wada, Takanari Ikeyama, Yoshinori Ito, Tomoo Ogi, Jun-ichi Kawada   +11 more
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An Introduction to Nanopore Sequencing: Past, Present, and Future Considerations

Micromachines, 2023
There has been significant progress made in the field of nanopore biosensor development and sequencing applications, which address previous limitations that restricted widespread nanopore use.
Morgan MacKenzie, Christos Argyropoulos
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Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era

The Innovation, 2021
Summary: The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies.
Shangqian Xie, Amy Wing-Sze Leung, Zhenxian Zheng, Dake Zhang, Chuanle Xiao, Ruibang Luo, Ming Luo, Shoudong Zhang   +7 more
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Freshwater monitoring by nanopore sequencing [PDF]

eLife, 2020
ABSTRACTWhile traditional microbiological freshwater tests focus on the detection of specific bacterial indicator species, including pathogens, direct tracing of all aquatic DNA through metagenomics poses a profound alternative. Yet,in situmetagenomic water surveys face substantial challenges in cost and logistics.
Urban, Lara, Holzer, Andre, Baronas, J Jotautas, Hall, Michael, Braeuninger-Weimer, Philipp, Scherm, Michael J, Kunz, Daniel J, Perera, Surangi N, Martin-Herranz, Daniel E, Tipper, Edward T, Salter, Susannah J, Stammnitz, Maximilian R   +11 more
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The Power of Using Novel Nanopore Sequencing Technology for Diagnosis, Genomic and Pathological Studies of Covid-19 [PDF]

E3S Web of Conferences, 2021
The novel coronavirus disease 2019 (COVID‐19), originally identified in December 2019 Wuhan, China, has propagated to worldwide pandemic, causing many cases of death and morbidity.
Du Chenghao
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Nanopore Technology and Its Applications in Gene Sequencing

Biosensors, 2021
In recent years, nanopore technology has become increasingly important in the field of life science and biomedical research. By embedding a nano-scale hole in a thin membrane and measuring the electrochemical signal, nanopore technology can be used to ...
Bo Lin, Jianan Hui, Hongju Mao
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