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The Evolution of Nanopore Sequencing [PDF]

Frontiers in Genetics, 2015
The $1,000 Genome project has been drawing increasing attention since its launch a decade ago. Nanopore sequencing, the third-generation, is believed to be one of the most promising sequencing technologies to reach four gold standards set for the $1,000 ...
Yue eWang, Qiuping eYang, Zhimin eWang
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An Introduction to Nanopore Sequencing: Past, Present, and Future Considerations

Micromachines, 2023
There has been significant progress made in the field of nanopore biosensor development and sequencing applications, which address previous limitations that restricted widespread nanopore use.
Morgan MacKenzie, Christos Argyropoulos
doaj   +4 more sources

Nanopore sequencing technology and its applications

MedComm, 2023
Since the development of Sanger sequencing in 1977, sequencing technology has played a pivotal role in molecular biology research by enabling the interpretation of biological genetic codes.
Peijie Zheng, Chuntao Zhou, Yuemin Ding, Bin Liu, Liuyi Lu, Feng Zhu, Shiwei Duan   +6 more
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Nanopore Technology and Its Applications in Gene Sequencing

Biosensors, 2021
In recent years, nanopore technology has become increasingly important in the field of life science and biomedical research. By embedding a nano-scale hole in a thin membrane and measuring the electrochemical signal, nanopore technology can be used to ...
Bo Lin, Jianan Hui, Hongju Mao
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Recent advances in nanopore sequencing [PDF]

Electrophoresis, 2012
The prospect of nanopores as a next‐generation sequencing platform has been a topic of growing interest and considerable government‐sponsored research for more than a decade. Oxford Nanopore Technologies recently announced the first commercial nanopore sequencing devices, to be made available by the end of 2012, while other companies (Life, Roche, and ...
Raj D, Maitra, Jungsuk, Kim, William B, Dunbar   +2 more
exaly   +3 more sources

Three decades of nanopore sequencing [PDF]

Nature Biotechnology, 2016
A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule through that pore. With the development of enzyme-based methods that ratchet polynucleotides through the nanopore, nucleobase-by-nucleobase, measurements of changes in the current ...
Mark Akeson, David Deamer, Daniel Branton   +2 more
exaly   +3 more sources

Portable nanopore-sequencing technology: Trends in development and applications

Frontiers in Microbiology, 2023
Sequencing technology is the most commonly used technology in molecular biology research and an essential pillar for the development and applications of molecular biology.
Pin Chen, Zepeng Sun, Jiawei Wang, Xinlong Liu, Yun Bai, Jiang Chen, Anna Liu, Feng Qiao, Yang Chen, Chenyan Yuan, Jingjie Sha, Jinghui Zhang, Li-Qun Xu, Jian Li   +13 more
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Following the central dogma: Nanopore sequencing from DNA and RNA to proteins [PDF]

iScience
Summary: The first nanopore-based sequencer was launched in 2014, and subsequently, nanopore played an irreplaceable role in disclosing the first complete, gapless sequence of a human genome in 2022 due to its megabase-scale read lengths.
Yutong Wang, Qian Han, Yilong He, Shumin Deng, Ziwei Huang, Ziyan Zhang, Shuaijian Dai, Zhuxin Dong   +7 more
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Utility of nanopore sequencing for detecting pathogens in bronchoalveolar lavage fluid from pediatric patients with respiratory failure

Journal of Clinical Virology Plus, 2023
RNA viruses are the most frequent pathogens responsible for respiratory infections, particularly in pediatric patients. Next-generation sequencing, represented by Illumina sequencing, is one of the most comprehensive methods for identifying pathogens ...
Makoto Yamaguchi, Kazuhiro Horiba, Kazunori Haruta, Suguru Takeuchi, Takako Suzuki, Yuka Torii, Shinji Kawabe, Sho Wada, Takanari Ikeyama, Yoshinori Ito, Tomoo Ogi, Jun-ichi Kawada   +11 more
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Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era

The Innovation, 2021
Summary: The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies.
Shangqian Xie, Amy Wing-Sze Leung, Zhenxian Zheng, Dake Zhang, Chuanle Xiao, Ruibang Luo, Ming Luo, Shoudong Zhang   +7 more
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