Results 31 to 40 of about 63,196 (293)

From squiggle to basepair: computational approaches for improving nanopore sequencing read accuracy

Genome Biology, 2018
Nanopore sequencing is a rapidly maturing technology delivering long reads in real time on a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this new way of sequencing and has used it successfully for a variety of ...
Franka J. Rang, Wigard P. Kloosterman, Jeroen de Ridder   +2 more
doaj   +1 more source

Application of nanopore adaptive sequencing in pathogen detection of a patient with Chlamydia psittaci infection

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionNanopore sequencing has been widely used in clinical metagenomic sequencing for pathogen detection with high portability and real-time sequencing.
Yanfeng Lin, Yanfeng Lin, Yan Dai, Shuang Zhang, Shuang Zhang, Hao Guo, Lang Yang, Jinhui Li, Kaiying Wang, Ming Ni, Ming Ni, Zongqian Hu, Zongqian Hu, Leili Jia, Huiying Liu, Peng Li, Hongbin Song, Hongbin Song   +17 more
doaj   +1 more source

Nanopore-based complete genome sequence of a Sri Lankan cassava mosaic virus (Geminivirus) strain from Thailand [PDF]

, 2020
Sri Lankan cassava mosaic virus is an emerging pathogen in Southeast Asia. Here, we report the complete genome of a Thai isolate obtained using Nanopore technology.
Barrantes, Israel, Cuellar, Wilmer J., Hemniam, Nuannapa, Leiva Sandoval, Ana Maria, Lopez-Alvarez, Diana, Saokham, Kingkan, Siriwan, Wanwisa   +6 more
core   +1 more source

NanoSTR: A method for detection of target short tandem repeats based on nanopore sequencing data

Frontiers in Molecular Biosciences, 2023
Short tandem repeats (STRs) are widely present in the human genome. Studies have confirmed that STRs are associated with more than 30 diseases, and they have also been used in forensic identification and paternity testing.
Jidong Lang, Zhihua Xu, Yue Wang, Jiguo Sun, Zhi Yang   +4 more
doaj   +1 more source

A Hybrid Sequencing Approach Completes the Genome Sequence of Thermoanaerobacter ethanolicus JW 200 [PDF]

, 2019
Thermoanaerobacter ethanolicus JW 200 has been identified as a potential sustainable biofuel producer due to its ability to readily ferment carbohydrates to ethanol. A hybrid sequencing approach, combining Oxford Nanopore and Illumina DNA sequence reads,
Ayine, Monica L., Gill, Steven R., Gilman, James A., Hewlett, Mark, James, Paul B.C., Love, John, Parker, David A., Power, Ann L., Singleton, Chloe, Tennant, Richard K.   +9 more
core   +1 more source

Nanopore Sequencing Technology and Tools for Genome Assembly: Computational Analysis of the Current State, Bottlenecks and Future Directions

, 2018
Nanopore sequencing technology has the potential to render other sequencing technologies obsolete with its ability to generate long reads and provide portability.
Alkan, Can, Cali, Damla Senol, Ghose, Saugata, Kim, Jeremie S., Mutlu, Onur   +4 more
core   +2 more sources

Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing. [PDF]

, 2020
Recent efforts to comprehensively characterize great ape genetic diversity using short-read sequencing and single-nucleotide variants have led to important discoveries related to selection within species, demographic history, and lineage-specific traits.
Andrés, Aida M, Dennis, Megan Y, Kaya, Gulhan, Mastoras, Mira, Sahasrabudhe, Ruta, Schmidt, Joshua M, Shew, Colin, Soto, Daniela C   +7 more
core   +3 more sources

De novo whole-genome assembly of a wild type yeast isolate using nanopore sequencing [version 2; referees: 1 approved, 3 approved with reservations]

F1000Research, 2018
Background: The introduction of the MinION sequencing device by Oxford Nanopore Technologies may greatly accelerate whole genome sequencing. Nanopore sequence data offers great potential for de novo assembly of complex genomes without using other ...
Michael Liem, Hans J. Jansen, Ron P. Dirks, Christiaan V. Henkel, G. Paul H. van Heusden, Richard J.L.F. Lemmers, Trifa Omer, Shuai Shao, Peter J. Punt, Herman P. Spaink   +9 more
doaj   +1 more source

Application of Nanopore Sequencing for High Throughput Genotyping in Horses

Animals, 2023
Nanopore sequencing is a third-generation biopolymer sequencing technique that relies on monitoring the changes in an electrical current that occur as nucleic acids are passed through a protein nanopore.
Artur Gurgul, Igor Jasielczuk, Tomasz Szmatoła, Sebastian Sawicki, Ewelina Semik-Gurgul, Bogusława Długosz, Monika Bugno-Poniewierska   +6 more
doaj   +1 more source

Recent progress in atomistic simulation of electrical current DNA sequencing

, 2014
We review recent advances in the DNA sequencing based on the measurement of transverse electrical currents. Device configurations proposed in the literature are classified according to whether the molecular fingerprints appear as the major (Mode I) or ...
Kim, Han Seul, Kim, Yong-Hoon
core   +1 more source