Results 1 to 10 of about 101,026 (352)
Rapid prenatal CNV detection using nanopore technology [PDF]
BMC Research NotesRapid identification of copy-number variations (CNVs) is crucial in prenatal diagnosis; however, current chromosomal microarray analysis (CMA) has a lengthy turnaround time. We evaluated the feasibility of low-pass nanopore sequencing for genome-wide CNV
Maolee Bhuwapathanapun +15 more
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Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis
Nature Communications, 2021 Nanopore sequencing technologies applied to transcriptome analysis suffer from high error rates, limiting them largely to reference-based analyses. Here, the authors develop a computational error correction method for transcriptome analysis that reduces ...
Kristoffer Sahlin +3 more
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Genome Biology, 2021 We develop the Oncogene Concatenated Enriched Amplicon Nanopore Sequencing (OCEANS) method, in which variants with low variant allele frequency (VAFs) are amplified and subsequently concatenated for Nanopore Sequencing.
Deepak Thirunavukarasu +8 more
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Recent advances in ionic current rectification based nanopore sensing: a mini-review
Sensors and Actuators Reports, 2021 In recent years, the intensive studies have been devoted to nanopores due to their unique charge transport properties including ion permselectivity, ion concentration polarization, and ionic current rectification (ICR).
Shujie Zhang +8 more
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Nanopore sequencing-based genome assembly and evolutionary genomics of circum-basmati rice
Genome Biology, 2020 Background The circum-basmati group of cultivated Asian rice (Oryza sativa) contains many iconic varieties and is widespread in the Indian subcontinent.
Jae Young Choi +8 more
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Single molecule sensing by nanopores and nanopore devices [PDF]
The Analyst, 2010 Molecular-scale pore structures, called nanopores, can be assembled by protein ion channels through genetic engineering or be artificially fabricated on solid substrates using fashion nanotechnology. When target molecules interact with the functionalized lumen of a nanopore, they characteristically block the ion pathway.
Li-Qun, Gu, Ji Wook, Shim
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Frontiers in Energy Research, 2021 Two-dimensional nanopores are very promising for high-permeance molecular sieving, but the molecular backflow from permeate-side to feed-side is not beneficial for improving molecular permeance.
Chengzhen Sun +3 more
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Pore Structures for High-Throughput Nanopore Devices
Micromachines, 2020 Nanopore devices are expected to advance the next-generation of nanobiodevices because of their strong sensing and analyzing capabilities for single molecules and bioparticles. However, the device throughputs are not sufficiently high.
Sou Ryuzaki +2 more
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Journal of Nanoscience and Nanotechnology, 2002 The current review article attempts to cover the field of nanoporous materials, thereby materials with voids of the order of 1 nm to 100 nm or even larger. Concepts, that have an effect on a more general basis, are introduced and the common features among the different classes of nanoporous materials are demonstrated enabling understanding their ...
Polarz, Sebastian, Smarsly, Bernd
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Barcode demultiplexing of nanopore sequencing raw signals by unsupervised machine learning
Frontiers in Bioinformatics, 2023 Introduction: Oxford Nanopore Technologies (ONT) is a third generation sequencing approach that allows the analysis of individual, full-length nucleic acids. ONT records the alterations of an ionic current flowing across a nano-scaled pore while a DNA or
Daniele M. Papetti +19 more
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