Results 1 to 10 of about 1,096,418 (305)
Indian Journal of Medical and Paediatric Oncology, 2020 Introduction microRNAs (miRNAs) have critical roles in tumorigenesis and cancer metastasis. Despite the importance of these small molecules, considerable number of miRNAs have not been identified or experimentally validated yet.
Guruprasad Bhat, Amit Kumar Jain
doaj +4 more sources
Next-generation sequencing [PDF]
Nature Reviews Drug Discovery, 2010 It has been widely appreciated that the genome sequence is shaping the future biomedical research. The genome sequence provides a general framework for assembling fragmentary DNA information into landscape of biological structure and function [1]. The rapid advances in DNA sequencing technology are revolutionizing biomedical research.
Xiong, Momiao +3 more
exaly +3 more sources
Sequencing technologies — the next generation [PDF]
Nature Reviews Genetics, 2010 (Uploaded by Plazi for the Bat Literature Project) No abstract provided.
M. Metzker
semanticscholar +4 more sources
Genesis of next-generation sequencing
Nature Biotechnology, 2023 The first large genome fully sequenced by next-generation sequencing (NGS) was that of a bacteriophage using sequencing by synthesis (SBS) as a paradigm. SBS in NGS is underpinned by ‘reversible-terminator chemistry’.
Raphaël Rodriguez, Y. Krishnan
semanticscholar +3 more sources
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021 Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
doaj +4 more sources
Next generation sequencing technologies for next generation plant breeding [PDF]
Frontiers in Plant Science, 2014 As a term, “next generation plant breeding” is increasingly becoming popular in crop breeding programmes, conferences, scientific fora and social media (Schnable, 2013). Being a frontier area of crop science and business, it is gaining considerable interest among scientific community and policymakers and funds flow from entrepreneurs and research ...
SOHAM eRAY, PRATIK eSATYA
doaj +3 more sources
Coming of age: ten years of next-generation sequencing technologies
Nature Reviews Genetics, 2016 John Mcpherson +2 more
exaly +2 more sources
Next generation sequencing in cytology [PDF]
Cytopathology, 2021 AbstractThe application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in ...
Pisapia, Pasquale +11 more
openaire +3 more sources
Demystifying the Discussion of Sequencing Panel Size in Oncology Genetic Testing
European Medical Journal, 2022 Clinical laboratories worldwide are implementing next-generation sequencing (NGS) to identify cancer genomic variants and ultimately improve patient outcomes. The ability to massively sequence the entire genome or exome of tumour cells has been critical
Cecília Durães +3 more
doaj +1 more source
Viruses, 2022 Viral respiratory infections contribute to significant morbidity and mortality in children. Currently, there are limited reports on the composition and abundance of the normal commensal respiratory virome in comparison to those in severe acute ...
Ayodeji E. Ogunbayo +5 more
doaj +1 more source