Results 11 to 20 of about 614,915 (309)

Next-generation sequencing [PDF]

Nature Reviews Drug Discovery, 2010
It has been widely appreciated that the genome sequence is shaping the future biomedical research. The genome sequence provides a general framework for assembling fragmentary DNA information into landscape of biological structure and function [1]. The rapid advances in DNA sequencing technology are revolutionizing biomedical research.
Xiong, Momiao, Zhao, Zhongming, Arnold, Jonathan, Yu, Fuli   +3 more
exaly   +3 more sources

Next generation sequencing

TATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021
Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society. New fields of research are emerging and questions of identity on the basis of genetic analyses are being negotiated.
Elsbeth Bösl, Stefanie Samida
doaj   +6 more sources

Next generation sequencing technologies for next generation plant breeding [PDF]

Frontiers in Plant Science, 2014
As a term, “next generation plant breeding” is increasingly becoming popular in crop breeding programmes, conferences, scientific fora and social media (Schnable, 2013). Being a frontier area of crop science and business, it is gaining considerable interest among scientific community and policymakers and funds flow from entrepreneurs and research ...
Ray, Soham, Satya, Pratik
openaire   +4 more sources

Next Generation Sequencing

Indian Journal of Medical and Paediatric Oncology, 2020
Guruprasad Bhat, Amit Kumar Jain
doaj   +4 more sources

Next generation sequencing in cytology [PDF]

Cytopathology, 2021
AbstractThe application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in ...
Pisapia, Pasquale, Pepe, Francesco, Sgariglia, Roberta, Nacchio, Mariantonia, Russo, Gianluca, Conticelli, Floriana, Girolami, Ilaria, Eccher, Albino, Bellevicine, Claudio, Vigliar, Elena, Malapelle, Umberto, Troncone, Giancarlo   +11 more
openaire   +3 more sources

Demystifying the Discussion of Sequencing Panel Size in Oncology Genetic Testing

European Medical Journal, 2022
Clinical laboratories worldwide are implementing next-generation sequencing (NGS) to identify cancer genomic variants and ultimately improve patient outcomes. The ability to massively sequence the entire genome or exome of tumour cells has been critical
Cecília Durães, Carla Pereira Gomes, Jose Luis Costa, Luca Quagliata   +3 more
doaj   +1 more source

Metagenomic Analysis of Respiratory RNA Virome of Children with and without Severe Acute Respiratory Infection from the Free State, South Africa during COVID-19 Pandemic Reveals Higher Diversity and Abundance in Summer Compared with Winter Period

Viruses, 2022
Viral respiratory infections contribute to significant morbidity and mortality in children. Currently, there are limited reports on the composition and abundance of the normal commensal respiratory virome in comparison to those in severe acute ...
Ayodeji E. Ogunbayo, Milton T. Mogotsi, Hlengiwe Sondlane, Kelebogile R. Nkwadipo, Saheed Sabiu, Martin M. Nyaga   +5 more
doaj   +1 more source

Next-generation sequencing demands next-generation phenotyping [PDF]

Human Mutation, 2012
Next-generation sequencing (NGS) is the most powerful diagnostic tool since the roentgenogram. NGS will facilitate diagnosis on a massive scale, allowing interrogation of all genes in a single assay. It has been suggested that NGS will decrease the need for phenotyping in general and medical geneticists in particular. We argue that NGS will shift focus
Hennekam, Raoul C. M., Biesecker, Leslie G.   +1 more
openaire   +3 more sources

In silico prediction of the enzymes involved in the degradation of the herbicide molinate by Gulosibacter molinativorax ON4T

Scientific Reports, 2022
Gulosibacter molinativorax ON4T is the only known organism to produce molinate hydrolase (MolA), which catalyses the breakdown of the thiocarbamate herbicide into azepane-1-carboxylic acid (ACA) and ethanethiol.
A. R. Lopes, E. Bunin, A. T. Viana, H. Froufe, A. Muñoz-Merida, D. Pinho, J. Figueiredo, C. Barroso, I. Vaz-Moreira, X. Bellanger, C. Egas, O. C. Nunes   +11 more
doaj   +1 more source

Transcriptomic studies reveal a key metabolic pathway contributing to a well-maintained photosynthetic system under drought stress in foxtail millet (Setaria italica L.) [PDF]

PeerJ, 2018
Drought stress is one of the most important abiotic factors limiting crop productivity. A better understanding of the effects of drought on millet (Setaria italica L.) production, a model crop for studying drought tolerance, and the underlying molecular ...
Weiping Shi, Jingye Cheng, Xiaojie Wen, Jixiang Wang, Guanyan Shi, Jiayan Yao, Liyuan Hou, Qian Sun, Peng Xiang, Xiangyang Yuan, Shuqi Dong, Pingyi Guo, Jie Guo   +12 more
doaj   +2 more sources