Results 11 to 20 of about 5,736,241 (346)

Next generation sequencing

open access: yesIndian Journal of Medical and Paediatric Oncology, 2020
Introduction microRNAs (miRNAs) have critical roles in tumorigenesis and cancer metastasis. Despite the importance of these small molecules, considerable number of miRNAs have not been identified or experimentally validated yet.
Guruprasad Bhat, Amit Kumar Jain
doaj   +3 more sources

Sequencing technologies — the next generation [PDF]

open access: yesNature Reviews Genetics, 2010
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
M. Metzker
semanticscholar   +4 more sources

Next-Generation Sequencing Technology: Current Trends and Advancements

open access: yesBiology, 2023
Simple Summary Next-generation sequencing (NGS) is a powerful tool used in genomics research. NGS can sequence millions of DNA fragments at once, providing detailed information about the structure of genomes, genetic variations, gene activity, and ...
Upasana Mangrolia   +2 more
exaly   +2 more sources

Next-generation sequencing [PDF]

open access: yesNature Reviews Drug Discovery, 2010
It has been widely appreciated that the genome sequence is shaping the future biomedical research. The genome sequence provides a general framework for assembling fragmentary DNA information into landscape of biological structure and function [1]. The rapid advances in DNA sequencing technology are revolutionizing biomedical research.
Xiong, Momiao   +3 more
exaly   +3 more sources

Genesis of next-generation sequencing

open access: yesNature Biotechnology, 2023
The first large genome fully sequenced by next-generation sequencing (NGS) was that of a bacteriophage using sequencing by synthesis (SBS) as a paradigm. SBS in NGS is underpinned by ‘reversible-terminator chemistry’.
Raphaël Rodriguez, Y. Krishnan
semanticscholar   +3 more sources

Next generation sequencing

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021
Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
doaj   +4 more sources

Next generation sequencing technologies for next generation plant breeding [PDF]

open access: yesFrontiers in Plant Science, 2014
As a term, “next generation plant breeding” is increasingly becoming popular in crop breeding programmes, conferences, scientific fora and social media (Schnable, 2013). Being a frontier area of crop science and business, it is gaining considerable interest among scientific community and policymakers and funds flow from entrepreneurs and research ...
SOHAM eRAY, PRATIK eSATYA
doaj   +3 more sources

Coming of age: ten years of next-generation sequencing technologies

open access: yesNature Reviews Genetics, 2016
John McPherson   +2 more
exaly   +2 more sources

Demystifying the Discussion of Sequencing Panel Size in Oncology Genetic Testing

open access: yesEuropean Medical Journal, 2022
Clinical laboratories worldwide are implementing next-generation sequencing (NGS) to identify cancer genomic variants and ultimately improve patient outcomes. The ability to massively sequence the entire genome or exome of tumour cells has been critical
Cecília Durães   +3 more
doaj   +1 more source

Next-generation sequencing [PDF]

open access: yesBreast Cancer Research, 2009
Next-generation sequencing (also known as massively parallel sequencing) technologies are revolutionising our ability to characterise cancers at the genomic, transcriptomic and epigenetic levels. Cataloguing all mutations, copy number aberrations and somatic rearrangements in an entire cancer genome at base pair resolution can now be performed in a ...
Atsushi, Toyoda, Asao, Fujiyama
openaire   +4 more sources

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