Results 11 to 20 of about 1,096,418 (305)
Microbial Genomics, 2022 Antimicrobial resistance (AMR) is one of the most important health threats globally. The ability to accurately identify resistant bacterial isolates and the individual antimicrobial resistance genes (ARGs) is essential for understanding the evolution and
A. F. Florensa +4 more
semanticscholar +1 more source
Next-generation sequencing demands next-generation phenotyping [PDF]
Human Mutation, 2012 Next-generation sequencing (NGS) is the most powerful diagnostic tool since the roentgenogram. NGS will facilitate diagnosis on a massive scale, allowing interrogation of all genes in a single assay. It has been suggested that NGS will decrease the need for phenotyping in general and medical geneticists in particular. We argue that NGS will shift focus
Hennekam, Raoul C. M. +1 more
openaire +3 more sources
Next-Generation Sequencing Technology: Current Trends and Advancements
Biology, 2023 Simple Summary Next-generation sequencing (NGS) is a powerful tool used in genomics research. NGS can sequence millions of DNA fragments at once, providing detailed information about the structure of genomes, genetic variations, gene activity, and ...
Heena Satam +10 more
semanticscholar +1 more source
Scientific Reports, 2022 Gulosibacter molinativorax ON4T is the only known organism to produce molinate hydrolase (MolA), which catalyses the breakdown of the thiocarbamate herbicide into azepane-1-carboxylic acid (ACA) and ethanethiol.
A. R. Lopes +11 more
doaj +1 more source
Transcriptomic studies reveal a key metabolic pathway contributing to a well-maintained photosynthetic system under drought stress in foxtail millet (Setaria italica L.) [PDF]
PeerJ, 2018 Drought stress is one of the most important abiotic factors limiting crop productivity. A better understanding of the effects of drought on millet (Setaria italica L.) production, a model crop for studying drought tolerance, and the underlying molecular ...
Weiping Shi +12 more
doaj +2 more sources
High-throughput Quant-iT PicoGreen assay using an automated liquid handling system
BioTechniques, 2019 Workflows in NGS facilities require high-standard practices and high-throughput pipelines to process the large number of samples received in a timely manner. Downstream protocols such as NGS library preparation require accurate estimation of nucleic acid
Kay Anantanawat +3 more
doaj +1 more source
CD-HIT: accelerated for clustering the next-generation sequencing data
Bioinform., 2012 Summary: CD-HIT is a widely used program for clustering biological sequences to reduce sequence redundancy and improve the performance of other sequence analyses.
Limin Fu +4 more
semanticscholar +1 more source
deepTools2: a next generation web server for deep-sequencing data analysis
Nucleic Acids Res., 2016 We present an update to our Galaxy-based web server for processing and visualizing deeply sequenced data. Its core tool set, deepTools, allows users to perform complete bioinformatic workflows ranging from quality controls and normalizations of aligned ...
Fidel Ramírez +8 more
semanticscholar +1 more source
Next-generation sequencing [PDF]
Breast Cancer Research, 2009 Next-generation sequencing (also known as massively parallel sequencing) technologies are revolutionising our ability to characterise cancers at the genomic, transcriptomic and epigenetic levels. Cataloguing all mutations, copy number aberrations and somatic rearrangements in an entire cancer genome at base pair resolution can now be performed in a ...
openaire +2 more sources
Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity
Cell Reports, 2023 Summary: Argonaute (AGO) proteins execute microRNA (miRNA)-mediated gene silencing. However, it is unclear whether all 4 mammalian AGO proteins (AGO1, AGO2, AGO3, and AGO4) are required for miRNA activity. We generate Ago1, Ago3, and Ago4-deficient mice (
Riccardo Guidi +19 more
doaj +1 more source