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Next-generation sequencing in dermatology
Frontiers in Medicine, 2023 Over the past decade, Next-Generation Sequencing (NGS) has advanced our understanding, diagnosis, and management of several areas within dermatology. NGS has emerged as a powerful tool for diagnosing genetic diseases of the skin, improving upon traditional PCR-based techniques limited by significant genetic heterogeneity associated with these disorders.
Andrew D. King +5 more
openaire +3 more sources
Viruses, 2020 Establishing a diverse gut microbiota after birth is essential for preventing illnesses later in life. However, little knowledge exists about the total viral population (virome) present in the gut of infants during the early developmental stage, with RNA
Milton T. Mogotsi +6 more
doaj +1 more source
Viruses, 2021 Rotarix® vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole genome sequencing and analysis.
Wairimu M. Maringa +7 more
doaj +1 more source
ANGSD: Analysis of Next Generation Sequencing Data
BMC Bioinformatics, 2014 High-throughput DNA sequencing technologies are generating vast amounts of data. Fast, flexible and memory efficient implementations are needed in order to facilitate analyses of thousands of samples simultaneously.
T. Korneliussen +2 more
semanticscholar +1 more source
Computational analysis of next generation sequencing data : from transcription start sites in bacteria to human non-coding RNAS [PDF]
, 2014 The advent of next generation sequencing (NGS) technologies has revolutionized the field of molecular biology by providing a wealth of sequence data. “Transcriptomics”, which aims to identify and annotate the complete set of RNA molecules transcribed ...
Jorjani, Hadi
core +1 more source
NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data
PLoS ONE, 2012 Next generation sequencing (NGS) technologies provide a high-throughput means to generate large amount of sequence data. However, quality control (QC) of sequence data generated from these technologies is extremely important for meaningful downstream ...
Ravi K. Patel, Mukesh Jain
semanticscholar +1 more source
Bioinformatics and Next- generation Sequencing [PDF]
Klinicka onkologie, 2015 Next-generation sequencing technologies are currently well-established in the research field and progressively find their way towards clinical applications. Sequencers produce vast amounts of data and therefore bioinformatics methods are needed for processing.
A, Krejčí, P, Müller, B, Vojtěšek
openaire +2 more sources
Genome Biology, 2009 Targeted RNA-Seq combines next-generation sequencing with capture of sequences from a relevant subset of a transcriptome. When testing by capturing sequences from a tumor cDNA library by hybridization to oligonucleotide probes specific for 467 cancer ...
J. Levin +8 more
semanticscholar +1 more source
Next-Generation Sequencing: Application in Liver Cancer—Past, Present and Future? [PDF]
, 2012 Hepatocellular Carcinoma (HCC) is the third most deadly malignancy worldwide characterized by phenotypic and molecular heterogeneity. In the past two decades, advances in genomic analyses have formed a comprehensive understanding of different underlying ...
Marquardt, Jens U +3 more
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Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center
Microbiome, 2019 Background Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
Aaron J. Prussin +6 more
doaj +1 more source