Results 61 to 70 of about 5,736,241 (346)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Virtual Environment for Next Generation Sequencing Analysis [PDF]

, 2012
Next Generation Sequencing technology, on the one hand, allows a more accurate analysis, and, on the other hand, increases the amount of data to process.
Provenzano, R., Provenzano R., Terzo, Olivier, Mossucca, L., Acquaviva, Andrea, Mossucca L, Abate, Francesco   +6 more
core  

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

BMC Bioinformatics, 2014
Adapter trimming is a prerequisite step for analyzing next-generation sequencing (NGS) data when the reads are longer than the target DNA/RNA fragments.
Hongshan Jiang, R. Lei, S. Ding, Shui-Fang Zhu   +3 more
semanticscholar   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Illuminating Choices for Library Prep: A Comparison of Library Preparation Methods for Whole Genome Sequencing of Cryptococcus neoformans Using Illumina HiSeq. [PDF]

, 2014
The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the major sequencing technology companies annually.
Mathew A Beale, Fisher, Matthew C, Rhodes Johanna, Matthew C Fisher, Rhodes, Johanna, Beale Mathew A., Fisher, MC, Beale, Mathew A, Fisher, Matthew C., Beale, Mathew A., Fisher Matthew C., Beale, MA, Rhodes, J, Johanna Rhodes, Rhodes, Johanna; id_orcid   +14 more
core   +1 more source

Accurate long-read transcript discovery and quantification at single-cell, pseudo-bulk and bulk resolution with Isosceles

Nature Communications
Accurate detection and quantification of mRNA isoforms from nanopore long-read sequencing remains challenged by technical noise, particularly in single cells. To address this, we introduce Isosceles, a computational toolkit that outperforms other methods
Michal Kabza, Alexander Ritter, Ashley Byrne, Kostianna Sereti, Daniel Le, William Stephenson, Timothy Sterne-Weiler   +6 more
doaj   +1 more source

Soil microbial load modulation improves plant–microbe interactions and bioinoculant efficacy in pathogen-stressed soils

Frontiers in Plant Science
Plants establish a close association with a community of microbes naturally living in the soil, known as resident soil microbiome, which typically maintains a dynamic equilibrium that confers resilience against biotic and abiotic perturbations.
Yohannes Ebabuye Andargie, Yohannes Ebabuye Andargie, GyuDae Lee, Min-Ji Kim, Eskindir Getachew Fentie, Minsoo Jeong, Setu Bazie Tagele, Kyeongmo Lim, Ugur Azizoglu, Ugur Azizoglu, Jae-Ho Shin, Jae-Ho Shin, Jae-Ho Shin   +12 more
doaj   +1 more source

Suppressing gain-of-function proteins via CRISPR/Cas9 system in SCA1 cells

Scientific Reports, 2022
SCAs are autosomal dominant neurodegenerative disorders caused by a gain-of-function protein with toxic activities, containing an expanded polyQ tract in the coding region.
Mariangela Pappadà, Ottavia Bonuccelli, Mattia Buratto, Riccardo Fontana, Mariaconcetta Sicurella, Anna Caproni, Silvia Fuselli, Andrea Benazzo, Roberto Bertorelli, Veronica De Sanctis, Paolo Cavallerio, Valentina Simioni, Valeria Tugnoli, Francesca Salvatori, Peggy Marconi   +14 more
doaj   +1 more source

The Role of Next Generation Sequencing in Genetic Counseling

, 2016
Genetic counseling is defined as a process that gives information about the risk of developing or transmitting a genetic condition to the next generation and management or treatment options of the genetic ailment.
Asude Durmaz, Durmaz A., Burak Durmaz, Durmaz B.   +3 more
core   +1 more source

Rapid Pathogen Detection by Metagenomic Next-Generation Sequencing of Infected Body Fluids

Nature Medicine, 2020
We developed a metagenomic next-generation sequencing (mNGS) test using cell-free DNA from body fluids to identify pathogens. The performance of mNGS testing of 182 body fluids from 160 patients with acute illness was evaluated using two sequencing ...
W. Gu, Xianding Deng, Marco B Lee, Yasemin Sucu, Shaun Arevalo, D. Stryke, Scot Federman, Allan Gopez, Kevin R. Reyes, K. Zorn, H. Sample, Guixia Yu, Gurpreet Ishpuniani, B. Briggs, Eric D. Chow, Amy Berger, M. Wilson, Candace Wang, Elaine D. Hsu, Steve Miller, J. Derisi, Charles Y. Chiu   +21 more
semanticscholar   +1 more source