Results 1 to 10 of about 1,415 (165)
BMC Bioinformatics, 2019 Background Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes.
Tobias Neumann +2 more
exaly +3 more sources
High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
Nature Communications, 2018 Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of ...
Ping Gao, Meijun Du, Sufyan Suleman
exaly +2 more sources
BMC Genomics, 2017 Background High throughput sequencing technology enables the both the human genome and transcriptome to be screened at the single nucleotide resolution. Tools have been developed to infer single nucleotide variants (SNVs) from both DNA and RNA sequencing
Yan Guo, Shilin Zhao, Quanhu Sheng
exaly +3 more sources
Plants, 2021 High-throughput sequencing from symptomatic tomato and pepper plants collected in Panama rendered the complete genome of the southern tomato virus (isolate STV_Panama) and bell pepper endornavirus (isolate BPEV_Panama), and almost-complete genomes of ...
L Galipienso +2 more
exaly +3 more sources
Current status of use of high throughput nucleotide sequencing in rheumatology
RMD Open, 2021 Objective Here, we assess the usage of high throughput sequencing (HTS) in rheumatic research and the availability of public HTS data of rheumatic samples.Methods We performed a semiautomated literature review on PubMed, consisting of an R-script and ...
Andreas Schwarting +2 more
doaj +1 more source
Microbiome Analysis Using Next-Generation Sequencing in Urinary Tract Infections [PDF]
Urogenital Tract Infection, 2022 In recent decades, the understanding of the genetic information of microbes and hosts has advanced considerably with the development of next-generation sequencing (NGS).
Hyunho Han, Joo Yong Lee
doaj +1 more source
Journal of Medical Signals and Sensors, 2021 Background: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis.
Hannane Mohammadi Nodehi +2 more
doaj +1 more source
Gene expression profile of Scardovia spp. in the metatranscriptome of root caries [PDF]
Brazilian Oral Research, 2020 A few investigations of caries biofilms have identified Scardovia spp.; however, little is known about its involvement in caries pathogenesis. The purpose of this study was to assess the gene expression profile of Scardovia spp.
Naile DAMÉ-TEIXEIRA +4 more
doaj +2 more sources
Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era [PDF]
Genomics & Informatics, 2013 Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques.
Mincheol Kim +5 more
doaj +1 more source
Nature Communications, 2023 There exist challenges in quantifying the length of individual telomeres at single nucleotide resolution. Here the authors report a method to capture telomeres and accurately analyse their length in human cell lines and patient peripheral blood leukocyte
Cheng-Yong Tham +18 more
doaj +1 more source