Results 1 to 10 of about 15,621,385 (284)
Background Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes.
Tobias Neumann +6 more
doaj +7 more sources
High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing [PDF]
Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of ...
Peng Zhang +16 more
doaj +8 more sources
Current status of use of high throughput nucleotide sequencing in rheumatology [PDF]
Objective Here, we assess the usage of high throughput sequencing (HTS) in rheumatic research and the availability of public HTS data of rheumatic samples.Methods We performed a semiautomated literature review on PubMed, consisting of an R-script and ...
Andreas Schwarting +2 more
doaj +5 more sources
The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data [PDF]
Background High throughput sequencing technology enables the both the human genome and transcriptome to be screened at the single nucleotide resolution. Tools have been developed to infer single nucleotide variants (SNVs) from both DNA and RNA sequencing
Yan Guo +4 more
doaj +6 more sources
Evaluation of MC1R high-throughput nucleotide sequencing data generated by the 1000 Genomes Project [PDF]
The advent of next-generation sequencing allows simultaneous processing of several genomic regions/individuals, increasing the availability and accuracy of whole-genome data. However, these new approaches may present some errors and bias due to alignment,
Leonardo Arduino Marano +3 more
doaj +7 more sources
Correction: Current status of use of high throughput nucleotide sequencing in rheumatology [PDF]
Boegel S, Castle JC, Schwarting A. Current status of use of high throughput nucleotide sequencing in rheumatology. RMD Open 2021;7:e001324. doi: 10.1136/rmdopen-2020-001324 The article has been …
doaj +5 more sources
Neuropeptidergic Signaling in the American Lobster Homarus americanus: New Insights from High-Throughput Nucleotide Sequencing. [PDF]
Peptides are the largest and most diverse class of molecules used for neurochemical communication, playing key roles in the control of essentially all aspects of physiology and behavior.
Andrew E Christie +7 more
doaj +5 more sources
High-throughput sequencing from symptomatic tomato and pepper plants collected in Panama rendered the complete genome of the southern tomato virus (isolate STV_Panama) and bell pepper endornavirus (isolate BPEV_Panama), and almost-complete genomes of ...
Luis Galipienso +4 more
doaj +3 more sources
Microbiome Analysis Using Next-Generation Sequencing in Urinary Tract Infections [PDF]
In recent decades, the understanding of the genetic information of microbes and hosts has advanced considerably with the development of next-generation sequencing (NGS).
Hyunho Han, Joo Yong Lee
doaj +1 more source
Background: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis.
Hannane Mohammadi Nodehi +2 more
doaj +1 more source

