Results 1 to 10 of about 4,822,162 (317)

“Genes” [PDF]

open access: yesTheory in Biosciences, 2008
In order to describe a cell at molecular level, a notion of a "gene" is neither necessary nor helpful. It is sufficient to consider the molecules (i.e., chromosomes, transcripts, proteins) and their interactions to describe cellular processes. The downside of the resulting high resolution is that it becomes very tedious to address features on the ...
Sonja J. Prohaska, Peter F. Stadler
openaire   +4 more sources

Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

open access: yesJournal of Neuroinflammation, 2023
Background Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more females than males.
Sarah R. Ocañas   +14 more
doaj   +1 more source

Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation

open access: yesJournal of Immunology Research, 2022
Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu   +7 more
doaj   +1 more source

Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis

open access: yesJournal of Immunology Research, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun   +8 more
doaj   +1 more source

Puncture, MRI and NMR relaxometry data for multiscale analysis of the degradation of apple structure due to thermal treatment

open access: yesData in Brief, 2021
The data presented here are related to the research paper entitled “Multiscale NMR analysis of the degradation of apple structure due to thermal treatment” whose aim was to investigate the critical temperature at which the cell membranes of a Golden ...
Alexandre Leca   +4 more
doaj   +1 more source

Gene Complexity and Gene Duplicability [PDF]

open access: yesCurrent Biology, 2005
Eukaryotic genes are on average more complex than prokaryotic genes in terms of expression regulation, protein length, and protein-domain structure [1-5]. Eukaryotes are also known to have a higher rate of gene duplication than prokaryotes do [6, 7]. Because gene duplication is the primary source of new genes [], the average gene complexity in a genome
He, Xionglei, Zhang, Jianzhi
openaire   +2 more sources

Characterization of integrated prophages within diverse species of clinical nontuberculous mycobacteria

open access: yesVirology Journal, 2020
Background Nontuberculous mycobacterial (NTM) infections are increasing in prevalence, with current estimates suggesting that over 100,000 people in the United States are affected each year.
Cody Glickman   +5 more
doaj   +1 more source

Analysis of Gene‐Gene Interactions [PDF]

open access: yesCurrent Protocols in Human Genetics, 2011
AbstractThe goal of this unit is to introduce gene‐gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene‐gene interactions and why they are likely to be common.
Diane, Gilbert-Diamond, Jason H, Moore
openaire   +2 more sources

A jornada da decisão do consumo de música na era digital por parte do consumidor jovem

open access: yesDiálogo com a Economia Criativa, 2020
Este artigo buscou analisar como se dá a jornada de decisão dos jovens cariocas com alto capital cultural, no que tange ao consumo de música popular. Mais especificamente, buscou-se identificar as etapas e influências que ocorrem na jornada de decisão ...
Cecilia Mattoso, Felipe Genes
doaj   +1 more source

Gene Activation and Gene Silencing [PDF]

open access: yesPlant Physiology, 2001
Twenty-five years ago the field of eukaryotic gene regulation was in its infancy. Paradigms driving experiments came primarily from work with prokaryotes and the phage that infected them (12). These paradigms, pioneered by Jacob and Monod, were that genes contained promoter sequences to which ...
V L, Chandler, H, Vaucheret
openaire   +2 more sources

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