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In order to describe a cell at molecular level, a notion of a "gene" is neither necessary nor helpful. It is sufficient to consider the molecules (i.e., chromosomes, transcripts, proteins) and their interactions to describe cellular processes. The downside of the resulting high resolution is that it becomes very tedious to address features on the ...
Sonja J. Prohaska, Peter F. Stadler
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Background Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more females than males.
Sarah R. Ocañas +14 more
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Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu +7 more
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Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun +8 more
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The data presented here are related to the research paper entitled “Multiscale NMR analysis of the degradation of apple structure due to thermal treatment” whose aim was to investigate the critical temperature at which the cell membranes of a Golden ...
Alexandre Leca +4 more
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Gene Complexity and Gene Duplicability [PDF]
Eukaryotic genes are on average more complex than prokaryotic genes in terms of expression regulation, protein length, and protein-domain structure [1-5]. Eukaryotes are also known to have a higher rate of gene duplication than prokaryotes do [6, 7]. Because gene duplication is the primary source of new genes [], the average gene complexity in a genome
He, Xionglei, Zhang, Jianzhi
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Background Nontuberculous mycobacterial (NTM) infections are increasing in prevalence, with current estimates suggesting that over 100,000 people in the United States are affected each year.
Cody Glickman +5 more
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Analysis of Gene‐Gene Interactions [PDF]
AbstractThe goal of this unit is to introduce gene‐gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene‐gene interactions and why they are likely to be common.
Diane, Gilbert-Diamond, Jason H, Moore
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A jornada da decisão do consumo de música na era digital por parte do consumidor jovem
Este artigo buscou analisar como se dá a jornada de decisão dos jovens cariocas com alto capital cultural, no que tange ao consumo de música popular. Mais especificamente, buscou-se identificar as etapas e influências que ocorrem na jornada de decisão ...
Cecilia Mattoso, Felipe Genes
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Gene Activation and Gene Silencing [PDF]
Twenty-five years ago the field of eukaryotic gene regulation was in its infancy. Paradigms driving experiments came primarily from work with prokaryotes and the phage that infected them (12). These paradigms, pioneered by Jacob and Monod, were that genes contained promoter sequences to which ...
V L, Chandler, H, Vaucheret
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