Results 21 to 30 of about 4,979,257 (318)
Identification of protein coding genes in genomes with statistical functions based on the circular code [PDF]
, 2002 A new statistical approach using functions based on the circular code classifies correctly more than 93 % of bases in protein (coding) genes and non-coding genes of human sequences. Based on this statistical study, a research software called "Analysis of
Lacan, Jérôme +5 more
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Gene Dosage and Gene Duplicability [PDF]
Genetics, 2008 Abstract The evolutionary process leading to the fixation of newly duplicated genes is not well understood. It was recently proposed that the fixation of duplicate genes is frequently driven by positive selection for increased gene dosage (i.e., the gene dosage hypothesis), because haploinsufficient genes were reported to have more ...
Wenfeng, Qian, Jianzhi, Zhang
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The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence genes: response. [PDF]
, 2006 A response to Snyder LA, Saunders NJ: The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence genes.
Hinds Jason +5 more
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The Epidermis: Genes On – Genes Off
Journal of Investigative Dermatology, 1997 The epidermal keratinocyte stem cell is distinguished by a relatively undifferentiated phenotype and an ability to proliferate. As part of a carefully orchestrated process, the offspring of these stem cells lose the ability to proliferate and begin a process of morphologic and biochemical transformation that results in their conversion into corneocytes.
Eckert, Richard L. +3 more
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BMJ, 2003 To the Medical Research Council, currently enjoying the warmth of celebrations marking the 50th anniversary of Crick and Watson's discovery of the double helix at an MRC laboratory, last week's report by the House of Commons science and technology committee must have felt like a bucket of ice cold water.
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Gene-Gene and Gene-Environment Interactions in Mild Hyperhomocysteinemia [PDF]
Pathophysiology of Haemostasis and Thrombosis, 2003 Mild/moderate hyperhomocysteinemia (HHcy), a highly prevalent condition, is independently associated with an increased risk of arterial and venous thromboembolic diseases. Early reports of the association of mild/moderate HHcy with juvenile venous thromboembolism have shown familiarity for HHcy in relatives of index cases with thrombosis.
D'Angelo, Armando +2 more
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Nature Communications, 2022 Lipid metabolism regulates stem cell states and differentiation. Here, the authors demonstrate a requirement in planarians for Apolipoprotein B-mediated neutral lipid transport from intestinal stores to stem cells and their progeny during differentiation
Lily L. Wong +5 more
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SLC38A6 expression in macrophages exacerbates pulmonary inflammation
Respiratory Research, 2023 Pulmonary inflammation involves complex changes of the immune cells, in which macrophages play important roles and their function might be influenced by metabolism. Slc38a6 acts as a carrier of nutrient for macrophages (Mφ) to exert the function. In this
Yizhao Peng +10 more
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Biomolecules, 2022 Pathogenic missense variants in COCH are associated with DFNA9, an autosomal dominantly inherited type of progressive sensorineural hearing loss with or without vestibular dysfunction.
Sybren M. M. Robijn +9 more
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Gene–gene and gene–environment interactions in ulcerative colitis [PDF]
Human Genetics, 2013 Genome-wide association studies (GWAS) have identified at least 133 ulcerative colitis (UC) associated loci. The role of genetic factors in clinical practice is not clearly defined. The relevance of genetic variants to disease pathogenesis is still uncertain because of not characterized gene-gene and gene-environment interactions.
Ming-Hsi, Wang +7 more
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