Results 11 to 20 of about 4,822,162 (317)

Genes, genes, genes

open access: yesBMJ, 2003
To the Medical Research Council, currently enjoying the warmth of celebrations marking the 50th anniversary of Crick and Watson's discovery of the double helix at an MRC laboratory, last week's report by the House of Commons science and technology committee must have felt like a bucket of ice cold water.
G. Watts, Watts, Geoff
openaire   +3 more sources

Acknowledgment to Reviewers of Genes in 2020

open access: yes, 2021
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Genes maintains its standards for the high quality of its published papers [...
Genes Editorial Office Genes Editorial Office
core   +1 more source

Rapidly evolving genes and stress adaptation of two desert poplars, Populus euphratica and P. pruinosa [PDF]

open access: yes, 2013
Understanding which genes have evolved rapidly with the recent tree speciation in arid habitats can provide valuable insights into different adaptation mechanisms. We employed a comparative evolutionary analysis of expressed sequence tags (ESTs) from two
Penghui Xie (420345)   +21 more
core   +1 more source

Comprehensive genomic profile of heterogeneous long follow-up triple-negative breast cancer and its clinical characteristics shows DNA repair deficiency has better prognostic [PDF]

open access: yes, 2020
Triple-negative breast cancer (TNBC) presents a marked diversity at the molecular level, which promotes a clinical heterogeneity that further complicates treatment.
Rosalía Quezada-Urban   +58 more
core   +1 more source

Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

open access: yesNature Communications, 2020
Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft ...
Katherine C. Goldfarbmuren   +11 more
doaj   +1 more source

FlyBase: genes and gene models [PDF]

open access: yesNucleic Acids Research, 2004
FlyBase (http://flybase.org) is the primary repository of genetic and molecular data of the insect family Drosophilidae. For the most extensively studied species, Drosophila melanogaster, a wide range of data are presented in integrated formats.
Rachel A. Drysdale, Madeline A. Crosby
openaire   +2 more sources

ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences [PDF]

open access: yes, 2004
A computer program, ARAGORN, identifies tRNA and tmRNA genes. The program employs heuristic algorithms to predict tRNA secondary structure, based on homology with recognized tRNA consensus sequences and ability to form a base-paired cloverleaf.
Laslett, D.   +4 more
core   +1 more source

Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools

open access: yesScientific Reports, 2017
Genetic access to small, reproducible sets of neurons is key to an understanding of the functional wiring of the brain. Here we report the generation of a new Gal4- and Cre-driver resource for zebrafish neurobiology.
Dominique Förster   +14 more
doaj   +1 more source

Simulation study and comparative evaluation of viral contiguous sequence identification tools

open access: yesBMC Bioinformatics, 2021
Background Viruses, including bacteriophages, are important components of environmental and human associated microbial communities. Viruses can act as extracellular reservoirs of bacterial genes, can mediate microbiome dynamics, and can influence the ...
Cody Glickman   +2 more
doaj   +1 more source

Gene Dosage and Gene Duplicability [PDF]

open access: yesGenetics, 2008
Abstract The evolutionary process leading to the fixation of newly duplicated genes is not well understood. It was recently proposed that the fixation of duplicate genes is frequently driven by positive selection for increased gene dosage (i.e., the gene dosage hypothesis), because haploinsufficient genes were reported to have more ...
Wenfeng, Qian, Jianzhi, Zhang
openaire   +2 more sources

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