Utilization of high throughput genome sequencing technology for large scale single nucleotide polymorphism discovery in red deer and Canadian elk [PDF]
bioRxiv, 2015 Deer farming is a significant international industry. For genetic improvement, using genomic tools, an ordered array of DNA variants and associated flanking sequence across the genome is required.
R. Brauning +8 more
semanticscholar +2 more sources
Journal of Medical Signals and Sensors, 2021 Background: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis.
Hannane Mohammadi Nodehi +2 more
doaj +1 more source
Microbiome Analysis Using Next-Generation Sequencing in Urinary Tract Infections [PDF]
Urogenital Tract Infection, 2022 In recent decades, the understanding of the genetic information of microbes and hosts has advanced considerably with the development of next-generation sequencing (NGS).
Hyunho Han, Joo Yong Lee
doaj +1 more source
Targeted High-Throughput Sequencing Enables the Detection of Single Nucleotide Variations in CRISPR/Cas9 Gene-Edited Organisms [PDF]
Foods, 2023 Similar to genetically modified organisms (GMOs) produced by classical genetic engineering, gene-edited (GE) organisms and their derived food/feed products commercialized on the European Union market fall within the scope of European Union Directive 2001/18/EC.
Marie-Alice Fraiture +9 more
openaire +5 more sources
Gene expression profile of Scardovia spp. in the metatranscriptome of root caries [PDF]
Brazilian Oral Research, 2020 A few investigations of caries biofilms have identified Scardovia spp.; however, little is known about its involvement in caries pathogenesis. The purpose of this study was to assess the gene expression profile of Scardovia spp.
Naile DAMÉ-TEIXEIRA +4 more
doaj +2 more sources
Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era [PDF]
Genomics & Informatics, 2013 Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques.
Mincheol Kim +5 more
doaj +1 more source
Diverse and widespread contamination evident in the unmapped depths of high throughput sequencing data [PDF]
, 2014 Background: Trace quantities of contaminating DNA are widespread in the laboratory environment, but their presence has received little attention in the context of high throughput sequencing.
Lusk, Richard W
core +9 more sources
Nucleic Acids Res., 2022 Antimicrobial resistance (AMR) is considered a critical threat to public health, and genomic/metagenomic investigations featuring high-throughput analysis of sequence data are increasingly common and important.
N. Bonin +10 more
semanticscholar +1 more source
Search for Novel Mutational Targets in Human Endocrine Diseases [PDF]
Endocrinology and Metabolism, 2019 The identification of disease-causing genetic variations is an important goal in the field of genetics. Advancements in genetic technology have changed scientific knowledge and made it possible to determine the basic mechanism and pathogenesis of human ...
So Young Park +2 more
doaj +1 more source
Optimization of conditions for in vitro modeling of subgingival normobiosis and dysbiosis
Frontiers in Microbiology, 2022 Modeling subgingival microbiome in health and disease is key to identifying the drivers of dysbiosis and to studying microbiome modulation. Here, we optimize growth conditions of our previously described in vitro subgingival microbiome model. Subgingival
Divyashri Baraniya +7 more
doaj +1 more source