Results 41 to 50 of about 373,405 (315)

Clinical features of Streptococcus intermedius infection in children: a case series study

open access: yesFrontiers in Microbiology, 2023
IntroductionStreptococcus intermedius is an opportunistic pathogen associated with prolonged hospital stays and high mortality rates in adults. However, little is currently known about the clinical features of Streptococcus intermedius infection in ...
Zhufei Xu   +5 more
doaj   +1 more source

Wheat rusts never sleep but neither do sequencers: will pathogenomics transform the way plant diseases are managed? [PDF]

open access: yes, 2015
Field pathogenomics adds highly informative data to surveillance surveys by enabling rapid evaluation of pathogen variability, population structure and host ...
Derevnina, Lida, Michelmore, Richard W
core   +2 more sources

Introducing SPeDE : high-throughput dereplication and accurate determination of microbial diversity from matrix-assisted laser desorption-ionization time of flight mass spectrometry data [PDF]

open access: yes, 2019
The isolation of microorganisms from microbial community samples often yields a large number of conspecific isolates. Increasing the diversity covered by an isolate collection entails the implementation of methods and protocols to minimize the number of ...
Aerts, Maarten   +13 more
core   +2 more sources

Detection of single nucleotide polymorphisms in virus genomes assembled from high-throughput sequencing data: large-scale performance testing of sequence analysis strategies

open access: yesPeerJ, 2023
Recent developments in high-throughput sequencing (HTS) technologies and bioinformatics have drastically changed research in virology, especially for virus discovery. Indeed, proper monitoring of the viral population requires information on the different isolates circulating in the studied area.
Rollin, Johan   +22 more
openaire   +10 more sources

Rapid, High-Throughput Identification of Anthrax-Causing and Emetic Bacillus cereus Group Genome Assemblies via BTyper, a Computational Tool for Virulence-Based Classification of Bacillus cereus Group Isolates by Using Nucleotide Sequencing Data

open access: yesApplied and Environmental Microbiology, 2017
The Bacillus cereus group comprises nine species, several of which are pathogenic. Differentiating between isolates that may cause disease and those that do not is a matter of public health and economic importance, but it can be particularly challenging ...
L. Carroll   +3 more
semanticscholar   +1 more source

A bioinformatics approach to microRNA-sequencing analysis

open access: yesOsteoarthritis and Cartilage Open, 2021
The rapid expansion of Next Generation Sequencing (NGS) data availability has made exploration of appropriate bioinformatics analysis pipelines a timely issue.
Pratibha Potla   +2 more
doaj   +1 more source

GlobalFungi, a global database of fungal occurrences from high-throughput-sequencing metabarcoding studies

open access: yesScientific Data, 2020
Fungi are key players in vital ecosystem services, spanning carbon cycling, decomposition, symbiotic associations with cultivated and wild plants and pathogenicity.
T. Větrovský   +32 more
semanticscholar   +1 more source

A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations [PDF]

open access: yesViruses, 2020
High-throughput sequencing such as those provided by Illumina are an efficient way to understand sequence variation within viral populations. However, challenges exist in distinguishing process-introduced error from biological variance, which significantly impacts our ability to identify sub-consensus single-nucleotide variants (SNVs).
David J. King   +7 more
openaire   +3 more sources

DUDE-Seq: Fast, flexible, and robust denoising for targeted amplicon sequencing. [PDF]

open access: yesPLoS ONE, 2017
We consider the correction of errors from nucleotide sequences produced by next-generation targeted amplicon sequencing. The next-generation sequencing (NGS) platforms can provide a great deal of sequencing data thanks to their high throughput, but the ...
Byunghan Lee   +3 more
doaj   +1 more source

BamView: visualizing and interpretation of next-generation sequencing read alignments. [PDF]

open access: yes, 2012
So-called next-generation sequencing (NGS) has provided the ability to sequence on a massive scale at low cost, enabling biologists to perform powerful experiments and gain insight into biological processes.
Berriman, Matthew   +5 more
core   +1 more source

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