Results 51 to 60 of about 15,621,385 (284)
High‐throughput capture of nucleotide sequence polymorphisms in three Brassica species (Brassicaceae) using DNA microarrays [PDF]
American Journal of Botany, 2012 • Premise of the study: To capture molecular markers that are applicable to environmental risk assessment of genetically modified oilseed rape, and to streamline their development, we screened variations in nucleotide sequences of three Brassica species by DNA microarray analysis.• Methods and Results: Using the Affymetrix GeneChip Arabidopsis ATH1 ...Toru, Nishizawa, Masanori, Tamaoki, Yukio, Kaneko, Mitsuko, Aono, Akihiro, Kubo, Hikaru, Saji, Nobuyoshi, Nakajima +6 moreopenaire +2 more sourcesDesign of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology [PDF]
, 2009 A systematic review of the literature was carried out to determine the evidence for the reliability and validity of the assessment methods used in veterinary medical education. The review followed the approach used by the Best Evidence Medical Education (Rothschild, M. F., Clark Richard, Milan, D., Ramos Antonio M., Mark S Hansen, Martien A M Groenen, Affara, Nabeel A., Law, Andy S., Taylor, Jeremy F., Antonio M Ramos, Richard Clark, Andreia J Amaral, Schook Lawrence B., Megens, H.J.W.C., Max F. Rothschild, Crooijmans, Richard P.M.A., Bendixen, C., Taylor, J. F., Andy S Law, Denis Milan, Groenen, M.A.M., Robert D. Schnabel, Megens, H. J., Taylor Jeremy F., Hansen Mark S., Kerstens, H.H.D., Hansen, M. S., Crooijmans, R.P.M.A., Lawrence B Schook, Affara, N.A., Rohrer, Gary A., Tim P. L. Smith, Nabeel A. Affara, Tim P L Smith, Schnabel, R. D., Danny J Nonneman, Archibald Alan L., Law, A. S., Dehais Patrick, Nonneman Danny J., Law Andy S., Zhi-Liang Hu, Affara Nabeel A., Groenen, Martien A.M., Nonneman, Danny J., Archibald, A. L., Hedegaard Jakob, Ralph T Wiedmann, Danny J. Nonneman, Bendixen, Christian, Smith, T. P., Nabeel A Affara, Lawrence B. Schook, Hedegaard, Jakob, Crooijmans, R. P., Groenen, M. A., Carol Churcher, Hu, Z. L., Rohrer, G. A., Dehais, Patrice, Churcher, Carol, Clark, Richard, Megens, Hendrik-Jan, Hindrik H. Kerstens, Bendixen Christian, Beever, J. E., Churcher Carol, Amaral, Andreia J., Jeremy F Taylor, Zhi-Liang, Hu, Ralph T. Wiedmann, Gary A. Rohrer, Curt P. Van Tassell, Andy S. Law, Beever Jonathan E., Affara, N. A., Patrick Dehais, Rohrer Gary A., Dehais, P., Antonio M. Ramos, Gary A Rohrer, Ramos, A. M., Martien A. M. Groenen, Wiedmann, R. T., Kerstens, Hindrik H., Richard P. M. A. Crooijmans, Jakob Hedegaard, Churcher, C., Ramos, Antonio M., Hu Zhi-Liang, Kerstens Hindrik H., Alan L Archibald, Hansen, Mark S., Amaral, A. J., Schook, Lawrence B., Wiedmann Ralph T., Jonathan E. Beever, Milan Denis, Hedegaard, J., Christian Bendixen, Van Tassell Curt P., Mark S. Hansen, Kerstens, H. H., Andreia J. Amaral, Crooijmans Richard P. M. A., Groenen Martien A. M., Alan L. Archibald, Richard P M A Crooijmans, Amaral Andreia J., Jonathan E Beever, Rothschild, Max F., Rothschild Max F., Megens Hendrik-Jan, Smith, Tim P.L., Wiedmann, Ralph T., Jeremy F. Taylor, Clark, R., Milan, Denis, Archibald, Alan L., Nonneman, D. J., Hindrik H Kerstens, Schook, L. B., Hendrik-Jan Megens, Smith Tim P. L., Ramos, A., Van Tassell, Curt P., Beever, Jonathan E., Max F Rothschild, Schnabel Robert D., Robert D Schnabel, Amaral, A.J., Van Tassell, C. P., Curt P Van Tassell, Schnabel, Robert D. +133 morecore +1 more sourceStructural variation in the chicken genome identified by paired-end next-generation DNA sequencing of reduced representation libraries [PDF]
, 2011 Background Variation within individual genomes ranges from single nucleotide polymorphisms (SNPs) to kilobase, and even megabase, sized structural variants (SVs), such as deletions, insertions, inversions, and more complex rearrangements.Kerstens Hindrik HD, Vereijken, A., Martien AM Groenen, Bert W Dibbits, Groenen, M.A.M., Dibbits, B.W., Kerstens, H.H.D., Dibbits Bert W, Okimoto Ron, Hindrik HD Kerstens, Richard PMA Crooijmans, Addie Vereijken, Vereijken Addie, Crooijmans, R.P.M.A., Okimoto, R., Groenen Martien AM, Crooijmans Richard PMA, Ron Okimoto +17 morecore +2 more sourcesHigh-throughput SuperSAGE for digital gene expression analysis of multiple samples using next generation sequencing [PDF]
, 2010 We established a protocol of the SuperSAGE technology combined with next-generation sequencing, coined "High- Throughput (HT-) SuperSAGE". SuperSAGE is a method of digital gene expression profiling that allows isolation of 26-bp tag fragments from ...Schroth, G.P., Terauchi, Ryohei, Hideo Matsumura, Schroth Gary P, Krüger Detlev H., Kentaro Yoshida, Kahl, Guenter, Kahl, G., Fujibe, Takahiro, Krueger, Detlev H, Takahiro Fujibe, Luo, Shujun, Fujibe, T., Terauchi Ryohei, Eiji Kimura, Barrero, Roberto A, Yoshida Kentaro, Luo, S., Barrero Roberto A, Terauchi Ryohei, Albertyn Zayed, Luo, Shujun, Shujun Luo, Kimura, Eiji, Barrero, R.A., Schroth, Gary P., Terauchi, Ryohei, Detlev H Krüger, Yoshida Kentaro, Albertyn, Z., Ryohei Terauchi, Roberto A Barrero, Yoshida, Kentaro, Kahl Günter, Matsumura, Hideo, Luo Shujun, Krueger Detlev H, Albertyn Zayed, Gary P. Schroth, Kahl Guenter, Matsumura, Hideo, Fujibe Takahiro, Matsumura Hideo, Yoshida, K., Fujibe, Takahiro, Schroth Gary P., Krüger, D.H., Kahl, Günter, Luo Shujun, Krüger, Detlev H., Kimura, Eiji, Gary P Schroth, Albertyn, Zayed, Matsumura Hideo, Barrero Roberto A., Schroth, Gary P, Zayed Albertyn, Kimura, E., Terauchi, R., Kimura Eiji, Detlev H. Krüger, Albertyn, Zayed, Matsumura, H., Yoshida, Kentaro, Fujibe Takahiro, Barrero, Roberto A., Kimura Eiji, Roberto A. Barrero, Günter Kahl +68 morecore +1 more sourceConstruction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type I diabetes. [PDF]
, 2005 BACKGROUND: One strategy to help identify susceptibility genes for complex, multifactorial diseases is to map disease loci in a representative animal model of the disorder. The nonobese diabetic (NOD) mouse is a model for human type 1 diabetes.Undlien, Dag E, Lowe, C, Chamberlain, G, Savage, DA, Undlien, DE, Wicker, LS, Hunter, Kara M, Walker Neil, Wicker Linda S, Ionescu-Tîrgovişte, Constantin, Maier, Lisa M, Savage, David A, Fraser, H, Guja Cristian, Nutland Sarah, Vella, Adrian, Fraser, Heather, Nutland, Sarah, Moule, Carolyn, Payne, Felicity, Nutland, S, Maier, LM, Todd John A, Twells Rebecca C, Guja, Cristian, Twells, RC, Cooper, Jason D, Ionescu-Tîrgovişte Constantin, Maier Lisa M, Rønningen, Kjersti S, Payne Felicity, Moule Carolyn, Savage David A, Pask, Rebecca, Smyth Deborah J, Strachan, David P, Chamberlain Giselle, Twells, Rebecca C, Smink, LJ, Todd, John A, Hulme, J, Hunter Kara M, Vella, A, Hulme John, Hunter, KM, Lowe, Christopher, Wicker, Linda S, Walker, N, Lowe Christopher, Smyth, DJ, Peterson, LB, Smink, Luc J, Rønningen, KS, Smyth, Deborah J, Cooper Jason D, Strachan David P, Ionescu-Tîrgoviste, C, Payne, F, Pask Rebecca, Strachan, DP, Undlien Dag E, Hulme, John, Vella Adrian, Guja, C, Smink Luc J, Pask, R, Walker, Neil, Moule, C, Todd, JA, Fraser Heather, Rønningen Kjersti S, Chamberlain, Giselle, Peterson Laurence B, Cooper, JD, Peterson, Laurence B +74 morecore +11 more sourcesDiversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.Ilaria Chiaradia, Madeline A. Lancasterwiley +1 more sourceBiochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target [PDF]
, 2014 The human pathogen Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis (TB), a disease with high worldwide mortality rates. Current treatment programs are under significant threat from multi-drug and extensively-drug resistant ...VijayaShankar Nataraj, Reynolds Robert C., Nicholas J Loman, Lloyd, AJ, Besra, Gurdyal S., Klaus Fütterer, Ballell, L, Reynolds, Robert C., Abrahams, Katherine A, Loman, Nicholas J., Hobrath Judith V., Gurcha Sudagar S., Alderwick, LJ, Abrahams, Katherine A., Gurcha, SS, Cox, Jonathan A G, Abrahams Katherine A., Hobrath, JV, Loman, Nicholas J, Carlos Alemparte, Lluis Ballell, Bhatt, Apoorva; id_orcid, Cox Jonathan A. G., Loman, NJ, Besra, GS, Reynolds, Robert C, Alemparte Carlos, Alderwick, Luke J, Gurcha, Sudagar S, Besra, Gurdyal S; id_orcid, Abrahams, KA, Besra Gurdyal S., Hobrath, Judith V, Barros, D, Robert C Reynolds, Loman Nicholas J., Bhatt, A, Ballell, Lluis, Nataraj, VijayaShankar, Lloyd, Adrian J., Apoorva Bhatt, Bhatt Apoorva, Nataraj, V, Alemparte, Carlos, Lloyd, Adrian J, Fütterer, K, Hobrath, Judith V., Veeraraghavan Usha, Cox, Jonathan A. G., Cox, JA, Barros David, Veeraraghavan, Usha, Bhatt, Apoorva, Adrian J Lloyd, Jonathan A G Cox, Usha, V, Gurdyal S Besra, David Barros, Lloyd Adrian J., Reynolds, RC, Alderwick, Luke J., Ballell Lluis, Usha Veeraraghavan, Fütterer Klaus, Barros, David, Nataraj, Vijaya-Shankar, Luke J Alderwick, Gurcha, Sudagar S., Alderwick Luke J., Judith V Hobrath, Sudagar S Gurcha, Usha, Veeraraghavan, Nataraj VijayaShankar, Alemparte, C, Fütterer, Klaus, Katherine A Abrahams +75 morecore +1 more sourceAn epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz +14 morewiley +1 more source