Results 11 to 20 of about 70,205 (303)

Recent advances in ionic current rectification based nanopore sensing: a mini-review

Sensors and Actuators Reports, 2021
In recent years, the intensive studies have been devoted to nanopores due to their unique charge transport properties including ion permselectivity, ion concentration polarization, and ionic current rectification (ICR).
Yuan-Di Zhao, Bo Liu
exaly   +3 more sources

Nanopore SimulatION – a raw data simulator for Nanopore Sequencing [PDF]

2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2018
Nanopore DNA sequencing enables the sequence determination of single DNA molecules up to 10,000 times longer than currently permitted by second-generation sequencing platforms. Nanopore sequencing gives real-time access to sequencing data and enables the detection of epigenetic modifications.
Christian Rohrandt, Nadine Kraft, Pay Gießelmann, Bjorn Brandl, Bernhard M. Schuldt, Ulrich Jetzek, Franz-Josef Müller   +6 more
openaire   +5 more sources

Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis

Nature Communications, 2021
Nanopore sequencing technologies applied to transcriptome analysis suffer from high error rates, limiting them largely to reference-based analyses. Here, the authors develop a computational error correction method for transcriptome analysis that reduces ...
Kristoffer Sahlin, Botond Sipos, Phillip L. James, Paul Medvedev   +3 more
doaj   +1 more source

Nanopore-Enabled Dark-Field Digital Sensing of Nanoparticles

, 2023
In this study, we use nanopore arrays as a platform for detecting and characterizing individual nanoparticles (NPs) in real time. Dark-field imaging of nanopores with dimensions smaller than the wavelength of light occurs under conditions where trans ...
Jarek Metro (16876737), Anthony J. Hoffman (4165585), Varun Mannam (11669200), Christiana Oh (11569486), Paul W. Bohn (1334772), Allison R Cutri (16876740), Scott Howard (4180093), Vignesh Sundaresan (3591446), Milan Palei (5051873)   +8 more
core   +2 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U-87 MG cells. [PDF]

FEBS Open Bio
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Gupta P, Furness SG, Gharbi T, De Paoli-Iseppi R, Joshi SS, Clark M, Hare DL, Wookey P.   +7 more
europepmc   +2 more sources

Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection

Genome Biology, 2021
We develop the Oncogene Concatenated Enriched Amplicon Nanopore Sequencing (OCEANS) method, in which variants with low variant allele frequency (VAFs) are amplified and subsequently concatenated for Nanopore Sequencing.
Deepak Thirunavukarasu, Lauren Y. Cheng, Ping Song, Sherry X. Chen, Mitesh J. Borad, Lawrence Kwong, Phillip James, Daniel J. Turner, David Yu Zhang   +8 more
doaj   +1 more source

Matched Oxford Nanopore Technologies and Bisulfite Sequencing of the GM24385 Cell Line

, 2022
One of the most widespread genomic modifications is 5-methylcytosine (5mC), which most frequently occurs at CpG dinucleotides. Compared to whole-genome bisulfite sequencing, the traditional method of 5mC detection, nanopore technology can offer many ...
Oxford Nanopore Technologies
core   +1 more source

Nanopore sequencing-based genome assembly and evolutionary genomics of circum-basmati rice

Genome Biology, 2020
Background The circum-basmati group of cultivated Asian rice (Oryza sativa) contains many iconic varieties and is widespread in the Indian subcontinent.
Jae Young Choi, Zoe N. Lye, Simon C. Groen, Xiaoguang Dai, Priyesh Rughani, Sophie Zaaijer, Eoghan D. Harrington, Sissel Juul, Michael D. Purugganan   +8 more
doaj   +1 more source

Nanoporous Materials

Journal of Nanoscience and Nanotechnology, 2002
The current review article attempts to cover the field of nanoporous materials, thereby materials with voids of the order of 1 nm to 100 nm or even larger. Concepts, that have an effect on a more general basis, are introduced and the common features among the different classes of nanoporous materials are demonstrated enabling understanding their ...
Polarz, Sebastian, Smarsly, Bernd
openaire   +4 more sources

Quasi-Unidirectional Transport Bilayer Two-Dimensional Nanopores for Highly-Efficient Molecular Sieving

Frontiers in Energy Research, 2021
Two-dimensional nanopores are very promising for high-permeance molecular sieving, but the molecular backflow from permeate-side to feed-side is not beneficial for improving molecular permeance.
Chengzhen Sun, Cheng Liu, Kailin Luo, Bofeng Bai   +3 more
doaj   +1 more source