Results 11 to 20 of about 73,616 (310)
Single molecule sensing by nanopores and nanopore devices [PDF]
The Analyst, 2010 Molecular-scale pore structures, called nanopores, can be assembled by protein ion channels through genetic engineering or be artificially fabricated on solid substrates using fashion nanotechnology. When target molecules interact with the functionalized lumen of a nanopore, they characteristically block the ion pathway.
Li-Qun, Gu, Ji Wook, Shim
openaire +2 more sources
De-novo Assembly of Limnospira fusiformis Using Ultra-Long Reads
Frontiers in Microbiology, 2021 The Limnospira genus is a recently established clade that is economically important due to its worldwide use in biotechnology and agriculture. This genus includes organisms that were reclassified from Arthrospira, which are commercially marketed as ...
McKenna Hicks +3 more
doaj +1 more source
MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets
Frontiers in Genetics, 2020 The direct RNA sequencing platform offered by Oxford Nanopore Technologies allows for direct measurement of RNA molecules without the need of conversion to complementary DNA, fragmentation or amplification.
Luca Cozzuto +12 more
doaj +1 more source
LAFITE Reveals the Complexity of Transcript Isoforms in Subcellular Fractions
Advanced Science, 2023 Characterization of the subcellular distribution of RNA is essential for understanding the molecular basis of biological processes. Here, the subcellular nanopore direct RNA‐sequencing (DRS) of four lung cancer cell lines (A549, H1975, H358, and HCC4006)
Jizhou Zhang +7 more
doaj +1 more source
Nature Communications, 2016 Pore-forming toxins act by forming oligomeric pores in lipid membranes. Here the authors report the crystal structure of the lysenin pore, providing insights into the assembly and function of the pore in addition to suggesting that its properties make ...
Marjetka Podobnik +18 more
doaj +1 more source
Genome Medicine, 2019 Background Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation.
Claudia M. B. Carvalho +21 more
doaj +1 more source
Frontiers in Genetics, 2020 During the carcinogenesis of cervical cancer, the DNA of human papillomavirus (HPV) is frequently integrated into the human genome, which might be a biomarker for the early diagnosis of cervical cancer.
Wenjuan Yang +10 more
doaj +1 more source
Zero-mode waveguides and nanopore-based sequencing technologies accelerate single-molecule studies
Biophysics and Physicobiology, 2022 Single-molecule technologies can provide detailed information regarding molecular mechanisms and interactions that cannot easily be studied on the bulk scale; generally, individual molecular behaviors cannot be distinguished, and only average ...
Ryo Iizuka +2 more
doaj +1 more source
Nanopore-Based Protein Identification
, 2022 The implementation of a reliable, rapid, inexpensive, and simple method for whole-proteome identification would greatly benefit cell biology research and clinical medicine.
Mazdak Afshar Bakshloo +13 more
core +1 more source
Nanopore-Based Proteolytic Reactor for Sensitive and Comprehensive Proteomic Analyses
, 2016 Various silica-based microreactors have been designed that use enzyme immobilization to address technical concerns in proteolysis including inefficient and incomplete protein digestion.
Jie Fan (258204) +8 more
core +2 more sources