Results 11 to 20 of about 101,026 (352)
Nanopore-Based Protein Identification.
The implementation of a reliable, rapid, inexpensive, and simple method for whole-proteome identification would greatly benefit cell biology research and clinical medicine.
Mazdak Afshar Bakshloo +6 more
semanticscholar +2 more sources
Nanopore SimulatION – a raw data simulator for Nanopore Sequencing [PDF]
Nanopore DNA sequencing enables the sequence determination of single DNA molecules up to 10,000 times longer than currently permitted by second-generation sequencing platforms. Nanopore sequencing gives real-time access to sequencing data and enables the detection of epigenetic modifications.
Christian Rohrandt +6 more
openaire +5 more sources
Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA molecules have led to substantial improvements in accuracy, read length and throughput.
Yunhao Wang +4 more
semanticscholar +1 more source
Long-read Oxford Nanopore sequencing has democratized microbial genome sequencing and enables the recovery of highly contiguous microbial genomes from isolates or metagenomes.
M. Sereika +6 more
semanticscholar +1 more source
Efficient assembly of nanopore reads via highly accurate and intact error correction
Long nanopore reads are advantageous in de novo genome assembly. However, nanopore reads usually have broad error distribution and high-error-rate subsequences.
Ying Chen +14 more
semanticscholar +1 more source
Nanopore-Enabled Dark-Field Digital Sensing of Nanoparticles
In this study, we use nanopore arrays as a platform for detecting and characterizing individual nanoparticles (NPs) in real time. Dark-field imaging of nanopores with dimensions smaller than the wavelength of light occurs under conditions where trans ...
Jarek Metro (16876737) +8 more
core +2 more sources
Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing
Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been difficult in part because a simple method to simultaneously quantify their abundance and chemical modifications is lacking.
M. Lucas +8 more
semanticscholar +1 more source
The long-read amplicon provides a species-level solution for the community. With the improvement of nanopore flowcells, the accuracy of Oxford Nanopore Technologies (ONT) R10.4.1 has been substantially enhanced, with an average of approximately 99%.
Tianyuan Zhang +6 more
semanticscholar +1 more source
Enzyme-less nanopore detection of post-translational modifications within long polypeptides
Means to sequence DNA and RNA quickly and cheaply have revolutionized biology and medicine. The ability to analyse cellular proteins and their millions of variants would be an advance of comparable importance, but requires a fresh technical approach.
Pablo Martin-Baniandres +6 more
semanticscholar +1 more source
Matched Oxford Nanopore Technologies and Bisulfite Sequencing of the GM24385 Cell Line
One of the most widespread genomic modifications is 5-methylcytosine (5mC), which most frequently occurs at CpG dinucleotides. Compared to whole-genome bisulfite sequencing, the traditional method of 5mC detection, nanopore technology can offer many ...
Oxford Nanopore Technologies
core +1 more source

