Results 11 to 20 of about 101,026 (352)

Nanopore-Based Protein Identification.

open access: yesJournal of the American Chemical Society, 2022
The implementation of a reliable, rapid, inexpensive, and simple method for whole-proteome identification would greatly benefit cell biology research and clinical medicine.
Mazdak Afshar Bakshloo   +6 more
semanticscholar   +2 more sources

Nanopore SimulatION – a raw data simulator for Nanopore Sequencing [PDF]

open access: yes2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2018
Nanopore DNA sequencing enables the sequence determination of single DNA molecules up to 10,000 times longer than currently permitted by second-generation sequencing platforms. Nanopore sequencing gives real-time access to sequencing data and enables the detection of epigenetic modifications.
Christian Rohrandt   +6 more
openaire   +5 more sources

Nanopore sequencing technology, bioinformatics and applications

open access: yesNature Biotechnology, 2021
Rapid advances in nanopore technologies for sequencing single long DNA and RNA molecules have led to substantial improvements in accuracy, read length and throughput.
Yunhao Wang   +4 more
semanticscholar   +1 more source

Oxford Nanopore R10.4 long-read sequencing enables the generation of near-finished bacterial genomes from pure cultures and metagenomes without short-read or reference polishing

open access: yesNature Methods, 2022
Long-read Oxford Nanopore sequencing has democratized microbial genome sequencing and enables the recovery of highly contiguous microbial genomes from isolates or metagenomes.
M. Sereika   +6 more
semanticscholar   +1 more source

Efficient assembly of nanopore reads via highly accurate and intact error correction

open access: yesNature Communications, 2021
Long nanopore reads are advantageous in de novo genome assembly. However, nanopore reads usually have broad error distribution and high-error-rate subsequences.
Ying Chen   +14 more
semanticscholar   +1 more source

Nanopore-Enabled Dark-Field Digital Sensing of Nanoparticles

open access: yes, 2023
In this study, we use nanopore arrays as a platform for detecting and characterizing individual nanoparticles (NPs) in real time. Dark-field imaging of nanopores with dimensions smaller than the wavelength of light occurs under conditions where trans ...
Jarek Metro (16876737)   +8 more
core   +2 more sources

Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

open access: yesNature Biotechnology, 2023
Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been difficult in part because a simple method to simultaneously quantify their abundance and chemical modifications is lacking.
M. Lucas   +8 more
semanticscholar   +1 more source

The newest Oxford Nanopore R10.4.1 full-length 16S rRNA sequencing enables the accurate resolution of species-level microbial community profiling

open access: yesApplied and Environmental Microbiology, 2023
The long-read amplicon provides a species-level solution for the community. With the improvement of nanopore flowcells, the accuracy of Oxford Nanopore Technologies (ONT) R10.4.1 has been substantially enhanced, with an average of approximately 99%.
Tianyuan Zhang   +6 more
semanticscholar   +1 more source

Enzyme-less nanopore detection of post-translational modifications within long polypeptides

open access: yesbioRxiv, 2023
Means to sequence DNA and RNA quickly and cheaply have revolutionized biology and medicine. The ability to analyse cellular proteins and their millions of variants would be an advance of comparable importance, but requires a fresh technical approach.
Pablo Martin-Baniandres   +6 more
semanticscholar   +1 more source

Matched Oxford Nanopore Technologies and Bisulfite Sequencing of the GM24385 Cell Line

open access: yes, 2022
One of the most widespread genomic modifications is 5-methylcytosine (5mC), which most frequently occurs at CpG dinucleotides. Compared to whole-genome bisulfite sequencing, the traditional method of 5mC detection, nanopore technology can offer many ...
Oxford Nanopore Technologies
core   +1 more source

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