Results 31 to 40 of about 70,205 (303)
Frontiers in Genetics, 2020 During the carcinogenesis of cervical cancer, the DNA of human papillomavirus (HPV) is frequently integrated into the human genome, which might be a biomarker for the early diagnosis of cervical cancer.
Wenjuan Yang +10 more
doaj +1 more source
Zero-mode waveguides and nanopore-based sequencing technologies accelerate single-molecule studies
Biophysics and Physicobiology, 2022 Single-molecule technologies can provide detailed information regarding molecular mechanisms and interactions that cannot easily be studied on the bulk scale; generally, individual molecular behaviors cannot be distinguished, and only average ...
Ryo Iizuka +2 more
doaj +1 more source
Pattern Recognition of microRNA Expression in Body Fluids using Nanopore Decoding at Sub-femtomolar Concentration [PDF]
, 2021 This paper describes nanopore decoding for microRNA (miRNA) expression patterns using DNA computing technology. miRNAs have shown promise as markers for cancer diagnosis due to their cancer type-specificity, and therefore simple strategies for miRNA ...
Ryuji, Kawano +2 more
core +2 more sources
The evolution of nanopore sequencing [PDF]
Frontiers in Genetics, 2015 The "$1000 Genome" project has been drawing increasing attention since its launch a decade ago. Nanopore sequencing, the third-generation, is believed to be one of the most promising sequencing technologies to reach four gold standards set for the "$1000 Genome" while the second-generation sequencing technologies are bringing about a revolution in life
Wang, Yue, Yang, Qiuping, Wang, Zhimin
openaire +3 more sources
Nanopore-Based Proteolytic Reactor for Sensitive and Comprehensive Proteomic Analyses
, 2016 Various silica-based microreactors have been designed that use enzyme immobilization to address technical concerns in proteolysis including inefficient and incomplete protein digestion.
Jie Fan (258204) +8 more
core +2 more sources
Universal Nanopore Platform Integrating Multiple Resistive Pulse Sensors into a Single Microfluidic Device [PDF]
, 2021 Resistive pulse sensors have been used to characterise everything from whole cells to small molecules. Their integration into microfluidic devices have simplified sample handling whilst increasing throughput.
Angelika , Holzinger +4 more
core +2 more sources
Modeling of single-particle translocation through a low-aspect-ratio nanopore
Journal of Biomechanical Science and Engineering, 2019 A theoretical model for the motion of tiny spherical particles in a nanopore device is developed. The nanopore has a low aspect ratio, and the particles have a radius slightly smaller than that of the nanopore.
Tetsuro TSUJI +2 more
doaj +1 more source
Extraction of Organic Compounds From Lacustrine Oil-Prone Shales and the Effect on Nanopore
Frontiers in Earth Science, 2022 Lacustrine oil-prone shale at the oil-generation stage develops a large number of nanopores; however, the influence of fluid–shale interactions on the nanopores of lacustrine shale is poorly understood.
Huairen Cao +5 more
doaj +1 more source
, 2018 These files contain the best nanopore-only assembly produced by ABruijn (pre-corrected + Nanopolish), Canu (Racon x2 + Nanopolish), Flye (pre-corrected + Nanopolish), Miniasm + Minimap (filtered to 100x coverage with Filtlong, Racon x5 + Nanopolish) and ...
Natalie Ring (5116013)
core +1 more source
Profiling single-molecule reaction kinetics under nanopore confinement [PDF]
, 2021 The development of single-molecule reaction inside nanoconfinement is benefit to study the intrinsic molecular mechanism of a complex chemical reaction.
Yi-Tao , Long +4 more
core +2 more sources