Results 31 to 40 of about 101,026 (352)
Carbon nanopores for DNA sequencing: a review on nanopore materials
Chemical Communications, 2023 Herein, we review the recent progress and achievements in carbon nanopore sequencing based on materials, including the selection of carbon nanomaterials, technologies for nanopore formation, and future perspectives of carbon nanopore sequencing.
Jing Xu, Xin Jiang, Nianjun Yang
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Nanopore sequencing technology and its applications
MedComm, 2023 Since the development of Sanger sequencing in 1977, sequencing technology has played a pivotal role in molecular biology research by enabling the interpretation of biological genetic codes.
Peijie Zheng +6 more
semanticscholar +1 more source
Nature Methods, 2021 Long-read sequencing has the potential to transform variant detection by reaching currently difficult-to-map regions and routinely linking together adjacent variations to enable read-based phasing.
Kishwar Shafin +13 more
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MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets
Frontiers in Genetics, 2020 The direct RNA sequencing platform offered by Oxford Nanopore Technologies allows for direct measurement of RNA molecules without the need of conversion to complementary DNA, fragmentation or amplification.
Luca Cozzuto +12 more
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LAFITE Reveals the Complexity of Transcript Isoforms in Subcellular Fractions
Advanced Science, 2023 Characterization of the subcellular distribution of RNA is essential for understanding the molecular basis of biological processes. Here, the subcellular nanopore direct RNA‐sequencing (DRS) of four lung cancer cell lines (A549, H1975, H358, and HCC4006)
Jizhou Zhang +7 more
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Targeted nanopore sequencing with Cas9-guided adaptor ligation
Nature Biotechnology, 2020 Despite recent improvements in sequencing methods, there remains a need for assays that provide high sequencing depth and comprehensive variant detection.
Timothy Gilpatrick +9 more
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Genome Medicine, 2019 Background Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation.
Claudia M. B. Carvalho +21 more
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Frontiers in Genetics, 2020 During the carcinogenesis of cervical cancer, the DNA of human papillomavirus (HPV) is frequently integrated into the human genome, which might be a biomarker for the early diagnosis of cervical cancer.
Wenjuan Yang +10 more
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Zero-mode waveguides and nanopore-based sequencing technologies accelerate single-molecule studies
Biophysics and Physicobiology, 2022 Single-molecule technologies can provide detailed information regarding molecular mechanisms and interactions that cannot easily be studied on the bulk scale; generally, individual molecular behaviors cannot be distinguished, and only average ...
Ryo Iizuka +2 more
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Nature Communications, 2016 Pore-forming toxins act by forming oligomeric pores in lipid membranes. Here the authors report the crystal structure of the lysenin pore, providing insights into the assembly and function of the pore in addition to suggesting that its properties make ...
Marjetka Podobnik +18 more
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