Results 51 to 60 of about 63,196 (293)

First-principles study of high conductance DNA sequencing with carbon nanotube electrodes [PDF]

, 2011
Rapid and cost-effective DNA sequencing at the single nucleotide level might be achieved by measuring a transverse electronic current as single-stranded DNA is pulled through a nano-sized pore.
C. D. Pemmaraju, H. Peng, I. Rungger, S. Sanvito, U. Schwingenschlögl, V. Meunier, X. Chen   +6 more
core   +2 more sources

Nanopore-Based Target Sequence Detection

PLOS ONE, 2016
The promise of portable diagnostic devices relies on three basic requirements: comparable sensitivity to established platforms, inexpensive manufacturing and cost of operations, and the ability to survive rugged field conditions. Solid state nanopores can meet all these requirements, but to achieve high manufacturing yields at low costs, assays must be
Trevor J Morin, Tyler Shropshire, Xu Liu, Kyle Briggs, Cindy Huynh, Vincent Tabard-Cossa, Hongyun Wang, William B Dunbar   +7 more
openaire   +4 more sources

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

Accurate Detection of HPV Integration Sites in Cervical Cancer Samples Using the Nanopore MinION Sequencer Without Error Correction

Frontiers in Genetics, 2020
During the carcinogenesis of cervical cancer, the DNA of human papillomavirus (HPV) is frequently integrated into the human genome, which might be a biomarker for the early diagnosis of cervical cancer.
Wenjuan Yang, Ying Liu, Ruyi Dong, Jia Liu, Jidong Lang, Jialiang Yang, Weiwei Wang, Jingjing Li, Bo Meng, Geng Tian, Geng Tian   +10 more
doaj   +1 more source

Evaluation of multiplex nanopore sequencing for Salmonella serotype prediction and antimicrobial resistance gene and virulence gene detection

Frontiers in Microbiology, 2023
In a previous study, Multiplex-nanopore-sequencing based whole genome sequencing (WGS) allowed for accurate in silico serotype prediction of Salmonella within one day for five multiplexed isolates, using both SISTR and SeqSero2.
Xingwen Wu, Hao Luo, Chongtao Ge, Feng Xu, Xiangyu Deng, Martin Wiedmann, Robert C. Baker, Abigail E. Stevenson, Guangtao Zhang, Silin Tang   +9 more
doaj   +1 more source

Complete Genome Sequence of the Citrobacter freundii Type Strain. [PDF]

, 2020
Citrobacter freundii is a species of facultative anaerobic Gram-negative bacteria of the family Enterobacteriaceae The complete genome is composed of a single chromosomal circle of 4,957,773 bp with a G+C content of 52%
Booth, Benjamin W, Celniker, Susan E, Hess, Becky M, Neff, Michael J, Park, Soo, Wan, Kenneth H   +5 more
core  

SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement

Advanced Functional Materials, EarlyView.
An enzyme‐catalyzed surface‐initiated atom transfer radical polymerization (SI‐bioATRP) of an anionic monomer within mesoporous silica particles, using hemoglobin as a catalyst, allows for controlling the location of the formed polymer via size‐exclusion effects between the nanopores and the biomacromolecules, thereby opening routes to functional ...
Oleksandr Wondra, Eleonora Ornati, Robert Lehn, Joanna J. Mikolei, Hergen Breitzke, Raheleh Pardehkhorram, Gerd Buntkowsky, Nico Bruns, Annette Andrieu‐Brunsen   +8 more
wiley   +1 more source

DNA Sequencing by Hexagonal Boron Nitride Nanopore: A Computational Study

Nanomaterials, 2016
The single molecule detection associated with DNA sequencing has motivated intensive efforts to identify single DNA bases. However, little research has been reported utilizing single-layer hexagonal boron nitride (hBN) for DNA sequencing.
Liuyang Zhang, Xianqiao Wang
doaj   +1 more source

Fundamental Bounds and Approaches to Sequence Reconstruction from Nanopore Sequencers [PDF]

, 2016
Nanopore sequencers are emerging as promising new platforms for high-throughput sequencing. As with other technologies, sequencer errors pose a major challenge for their effective use.
Duda, Jarek, Grama, Ananth, Szpankowski, Wojciech   +2 more
core  

Nanopore Sequencing with MspA [PDF]

Biophysical Journal, 2009
Nanopores may provide the basis for a high-speed and inexpensive de novo DNA sequencing technique that could revolutionize medical and biological science. In this technique, single-stranded DNA is electrophoretically translocated through a pore with inner dimensions similar to that of DNA.
Derrington, Ian, Butler, Tom, Pavlenok, M., Collins, Marcus, Niederweis, Michael, Gundlach, Jens   +5 more
openaire   +1 more source