Results 71 to 80 of about 63,196 (293)

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Detailed evaluation of data analysis tools for subtyping of bacterial isolates based on whole genome sequencing : Neisseria meningitidis as a proof of concept [PDF]

open access: yes, 2019
Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Bertrand, Sophie   +5 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

open access: yesAdvanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi   +4 more
wiley   +1 more source

Nanopore sequencing of cerebrospinal fluid of three patients with cryptococcal meningitis

open access: yesEuropean Journal of Medical Research, 2022
Background Cryptococcal meningitis (CM) has a high morbidity and mortality due to the low detection of Cryptococcus in cerebrospinal fluid (CSF) during the early stage of the disease with traditional methods.
Ke Jin   +13 more
doaj   +1 more source

Nanopore Sequencing Provides Rapid and Reliable Insight Into Microbial Profiles of Intensive Care Units

open access: yesFrontiers in Public Health, 2021
Fast and accurate identification of pathogens is an essential task in healthcare settings. Second-generation sequencing platforms such as Illumina have greatly expanded the capacity with which different organisms can be detected in hospital samples, and ...
Guilherme Marcelino Viana de Siqueira   +3 more
doaj   +1 more source

Improving sequencing by tunneling with multiplexing and cross-correlations

open access: yes, 2014
Sequencing by tunneling is a next-generation approach to read single-base information using electronic tunneling transverse to the single-stranded DNA (ssDNA) backbone while the latter is translocated through a narrow channel.
Balatsky, A. V.   +3 more
core   +1 more source

Porosity Engineering of MXene Architectures: Toward High‐Performance Aqueous Electrochemical Energy Storage

open access: yesAdvanced Materials, EarlyView.
This review systematically summarizes recent advances in porosity engineering of MXenes, with a focused discussion on their structure‐governed energy storage properties. A critical analysis of structure–property relationships is presented across alkali‐ion batteries, multivalent‐ion batteries, and supercapacitors.
Shude Liu   +8 more
wiley   +1 more source

Fabrication of Atomically Precise Nanopores in Hexagonal Boron Nitride [PDF]

open access: yes, 2017
We demonstrate the fabrication of individual nanopores in hexagonal boron nitride (hBN) with atomically precise control of the pore size. Previous methods of pore production in other 2D materials create pores of irregular geometry with imprecise ...
Aloni, Shaul   +6 more
core   +1 more source

Air monitoring by nanopore sequencing

open access: yesISME Communications
Abstract While the air microbiome and its diversity are essential for human health and ecosystem resilience, comprehensive air microbial diversity monitoring has remained rare, so that little is known about the air microbiome’s composition, distribution, or functionality.
Reska, T.T.M.   +11 more
openaire   +3 more sources

Rapid resistome mapping using nanopore sequencing [PDF]

open access: yesNucleic Acids Research, 2016
AbstractThe emergence of antibiotic resistance in human pathogens has become a major threat to modern medicine and in particular hospitalized patients. The outcome of antibiotic treatment can be affected by the composition of the gut resistome either by enabling resistance gene acquisition of infecting pathogens or by modulating the collateral effects ...
van der Helm, Eric   +5 more
openaire   +3 more sources

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