Results 91 to 100 of about 47,109 (297)

Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase

Genome Biology, 2021
The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing allele-specific methylation. However, there is currently no complete software for detecting SNPs, phasing
Vahid Akbari, Jean-Michel Garant, Kieran O’Neill, Pawan Pandoh, Richard Moore, Marco A. Marra, Martin Hirst, Steven J. M. Jones   +7 more
doaj   +1 more source

Self‐Assembled Calcite Architectures for Programmable Information Storage

Advanced Materials Technologies, EarlyView.
Programmable biomineralization enables the formation of 3D calcite architectures that encode information through spatially defined refractive‐index modulations. Data are written via laser‐directed mineralization, stored in stable voxelized mineral structures, and retrieved non‐destructively through optical diffraction, offering a pathway toward ultra ...
Congrui Jin, Yong Huang, Mehdi Ranjkesh Rashteh Roudi   +2 more
wiley   +1 more source

Using Nanopore sequencing to identify bacterial infection in joint replacements: A Preliminary study [PDF]

This project investigates if third-generation genomic sequencing can be used to identify the species of bacteria causing prosthetic joint infections (PJIs) at the time of revision surgery.
McDonald, Jamie, Cool, Paul, McCarthy, Helen, Wilkinson, Hollie, Hulme, Charlotte, Wright, Karina, Perry, Jade   +6 more
core   +1 more source

Nanopore-CMOS Interfaces for DNA Sequencing [PDF]

, 2016
DNA sequencers based on nanopore sensors present an opportunity for a significant break from the template-based incumbents of the last forty years. Key advantages ushered by nanopore technology include a simplified chemistry and the ability to interface ...
Chengjie Wang, Yiyun Huang, Ebrahim Ghafar-Zadeh, Sebastian Magierowski   +3 more
core   +1 more source

Nanopore sequencing technology in forensic science: status quo and tendency

Annals of Human Biology
Context Next-generation sequencing (NGS) is widely used in forensics for high throughput but limited by short reads and high non-batch testing costs. Third-generation sequencing (TGS), especially Oxford Nanopore Technologies (ONT) nanopore sequencing ...
Tianzhen Gao, Wang He, Xin Feng, Bing Long, Deming Zhang   +4 more
doaj   +1 more source

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

Advanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang, Xinyuan Ke, Andrew Heath, Richard J. Ball, Jiawei Xie, Jinchen Fan, Guisheng Li, Kevin Paine   +7 more
wiley   +1 more source

Stability and bandwidth investigation of alternative structures for nanopore sensors [PDF]

, 2010
The genetic information carriers, DNA molecules can be thought of as the blueprints of living organisms. This crucial functionality of the DNA mole- cules may explain the drive and momentum for DNA sequencing research.
Yemenicioglu, Sukru
core  

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

Selective Sequencing with Nanopore Technology: Adaptive Sampling as a Real-Time Enrichment Strategy for Nuclear DNA [PDF]

reservedThird-generation sequencing methods like Oxford Nanopore are opening new doors in genomics by enabling long-read DNA sequencing in real time. Adaptive sampling is one of the optional features offered by Nanopore sequencing, allowing selective ...
ELIAGIR, IPEK SUDE
core  

Nanopores: a sequencer in your backpack [PDF]

Nature Methods, 2015
It's been a long wait for nanopore sequencing technology. Over 1,000 labs are testing the first commercial device and publishing results. Researchers tell Nature Methods about their experiences putting these early instruments through their paces. And more technology is in the works.
openaire   +2 more sources