Results 61 to 70 of about 47,109 (297)

Filtered Nanopore sequencing read statistics. [PDF]

, 2019
Filtered Nanopore sequencing read statistics.
Taylor Sheahan (7037267), Rhys Hakstol (7037270), Hans-Joachim Wieden (1389963), Graeme D. Glaister (7037276), Senthilkumar Kailasam (7037273), Andrew J. Hudson (3275988)   +5 more
core   +1 more source

Comparative analysis of hybrid-SNP microarray and nanopore sequencing for detection of large-sized copy number variants in the human genome

Molecular Cytogenetics
Background Nanopore sequencing is a technology that holds great promise for identifying all types of human genome variations, particularly structural variations.
Catarina Silva, José Ferrão, Bárbara Marques, Sónia Pedro, Hildeberto Correia, Ana Valente, António Sebastião Rodrigues, Luís Vieira   +7 more
doaj   +1 more source

Evaluation of multiplex nanopore sequencing for Salmonella serotype prediction and antimicrobial resistance gene and virulence gene detection

Frontiers in Microbiology, 2023
In a previous study, Multiplex-nanopore-sequencing based whole genome sequencing (WGS) allowed for accurate in silico serotype prediction of Salmonella within one day for five multiplexed isolates, using both SISTR and SeqSero2.
Xingwen Wu, Hao Luo, Chongtao Ge, Feng Xu, Xiangyu Deng, Martin Wiedmann, Robert C. Baker, Abigail E. Stevenson, Guangtao Zhang, Silin Tang   +9 more
doaj   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Raw Nanopore sequencing read statistics. [PDF]

, 2019
Raw Nanopore sequencing read statistics.
Taylor Sheahan (7037267), Rhys Hakstol (7037270), Hans-Joachim Wieden (1389963), Graeme D. Glaister (7037276), Senthilkumar Kailasam (7037273), Andrew J. Hudson (3275988)   +5 more
core   +1 more source

Nanopore sequencing for smear-negative pulmonary tuberculosis—a multicentre prospective study in China

Annals of Clinical Microbiology and Antimicrobials
Purpose In this prospective study, the diagnosis accuracy of nanopore sequencing-based Mycobacterium tuberculosis (MTB) detection was determined through examining bronchoalveolar lavage fluid (BALF) samples from pulmonary tuberculosis (PTB) -suspected ...
Xiaojing Yan, Guoli Yang, Yunfei Wang, Yuqing Wang, Jie Cheng, Peisong Xu, Xiaoli Qiu, Lei Su, Lina Liu, Ruixue Geng, Yingxia You, Hui Liu, Naihui Chu, Li Ma, Wenjuan Nie   +14 more
doaj   +1 more source

Diagnostic value of a nanopore sequencing assay of bronchoalveolar lavage fluid in pulmonary tuberculosis

BMC Pulmonary Medicine, 2023
Background To determine the diagnostic accuracy of a nanopore sequencing assay of PCR products from a M. tuberculosis complex-specific region for testing of bronchoalveolar lavage fluid (BALF) samples or sputum samples from suspected pulmonary ...
Zhifeng Liu, Yang Yang, Qingfeng Wang, Lei Wang, Wenjuan Nie, Naihui Chu   +5 more
doaj   +1 more source

Nanopore Sequencing Provides Rapid and Reliable Insight Into Microbial Profiles of Intensive Care Units

Frontiers in Public Health, 2021
Fast and accurate identification of pathogens is an essential task in healthcare settings. Second-generation sequencing platforms such as Illumina have greatly expanded the capacity with which different organisms can be detected in hospital samples, and ...
Guilherme Marcelino Viana de Siqueira, Felipe Marcelo Pereira-dos-Santos, Rafael Silva-Rocha, María-Eugenia Guazzaroni   +3 more
doaj   +1 more source

Graphene Nanopores for Protein Sequencing [PDF]

Biophysical Journal, 2016
An inexpensive, reliable method for protein sequencing is essential to unraveling the biological mechanisms governing cellular behavior and disease. Current protein sequencing methods suffer from limitations associated with the size of proteins that can be sequenced, the time, and the cost of the sequencing procedures. This study reports the results of
Wilson, James, Sloman, Leila, He, Zhiren, Aksimentiev, Aleksei   +3 more
openaire   +3 more sources

Error-Correcting Codes for Nanopore Sequencing

2023 IEEE International Symposium on Information Theory (ISIT), 2023
Submitted to Transactions on Information ...
Anisha Banerjee, Yonatan Yehezkeally, Antonia Wachter-Zeh, Eitan Yaakobi   +3 more
openaire   +3 more sources