Results 21 to 30 of about 938,732 (287)

Genotyping of familial Mediterranean fever gene (MEFV)—Single nucleotide polymorphism—Comparison of Nanopore with conventional Sanger sequencing

PLoS ONE, 2022
Background Through continuous innovation and improvement, Nanopore sequencing has become a powerful technology. Because of its fast processing time, low cost, and ability to generate long reads, this sequencing technique would be particularly suitable ...
Jonas Schmidt, Sandro Berghaus, Frithjof Blessing, Holger Herbeck, Josef Blessing, Peter Schierack, Stefan Rödiger, Dirk Roggenbuck, Folker Wenzel   +8 more
doaj   +2 more sources

The potential and challenges of nanopore sequencing [PDF]

Nature Biotechnology, 2008
A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore. The nanopore provides a highly confined space within which single nucleic acid polymers can be analyzed at high throughput by one of a variety of means, and the perfect ...
Branton, Daniel, Pershin, Yuriy V, Deamer, David W, Ling, Xinsheng Sean, Wiggin, Matthew, Lindsay, Stuart, Krstic, Predrag S, Huang, Xiaohua, Jovanovich, Stevan B, Butler, Thomas, Soni, Gautam V, Schloss, Jeffery A, Riehn, Robert, Hibbs, Andrew, Tabard-Cossa, Vincent, Wanunu, Meni, Bayley, Hagan, Marziali, Andre, Ramsey, J Michael, Mastrangelo, Carlos H, Meller, Amit, Benner, Steven A, Oliver, John S, Garaj, Slaven, Di Ventra, Massimiliano   +24 more
openaire   +4 more sources

Adaptation of Oxford Nanopore technology for hepatitis C whole genome sequencing and identification of within-host viral variants

BMC Genomics, 2021
Background Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advances in next ...
Nasir Riaz, Preston Leung, Kirston Barton, Martin A. Smith, Shaun Carswell, Rowena Bull, Andrew R. Lloyd, Chaturaka Rodrigo   +7 more
doaj   +1 more source

Interchromosomal template-switching as a novel molecular mechanism for imprinting perturbations associated with Temple syndrome

Genome Medicine, 2019
Background Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation.
Claudia M. B. Carvalho, Zeynep Coban-Akdemir, Hadia Hijazi, Bo Yuan, Matthew Pendleton, Eoghan Harrington, John Beaulaurier, Sissel Juul, Daniel J. Turner, Rupa S. Kanchi, Shalini N. Jhangiani, Donna M. Muzny, Richard A. Gibbs, Baylor-Hopkins Center for Mendelian Genomics, Pawel Stankiewicz, John W. Belmont, Chad A. Shaw, Sau Wai Cheung, Neil A. Hanchard, V. Reid Sutton, Patricia I. Bader, James R. Lupski   +21 more
doaj   +1 more source

Nanopore sequencing data of transconjugants

, 2023
Nanopore sequencing data of transconjugants.
yan li (6186836)
core   +1 more source

Nanopore sequencing in non-human forensic genetics [PDF]

, 2021
:The past decade has seen a rapid expansion of non-human forensic genetics coinciding with the development of 2nd and 3rd generation DNA sequencing technologies.
Vasiljevic, Nina, Ogden, Rob, Ogden, Rob; https://orcid.org/, Prost, Stefan, Vasiljevic, Nina; https://orcid.org/, Stefan Prost, Nina Vasiljevic, Rob Ogden   +7 more
core   +1 more source

Direct oligonucleotide sequencing with nanopores [PDF]

Open Research Europe, 2020
Third-generation DNA sequencing has enabled sequencing of long, unamplified DNA fragments with minimal steps. Direct sequencing of ssDNA or RNA gives valuable insights like base-level modifications, phosphoramidite synthesis yield estimates and strand quality analysis, without the need to add the complimentary strand.
Chalapati, Sachin, Crosbie, Conor A, Limbachiya, Dixita, Pinnamaneni, Nimesh   +3 more
openaire   +4 more sources

Nanopore sequencing statistics for T7 SDA reactions.

, 2022
Nanopore sequencing statistics for T7 SDA reactions.
Nathan A. Tanner (9400708), Dillon B. Nye (1327863)   +1 more
core   +1 more source

Kits and program versions for Nanopore sequencing.

, 2023
Kits and program versions for Nanopore sequencing.
Frank R. Bengelsdorf (6704159), Tim Böer (7041059), Mechthild Bömeke (14819938), Rolf Daniel (113374), Anja Poehlein (113372)   +4 more
core   +1 more source

Simulation of Nanopore Sequencing Signals Based on BiGRU

Sensors, 2020
Oxford Nanopore sequencing is an important sequencing technology, which reads the nucleotide sequence by detecting the electrical current signal changes when DNA molecule is forced to pass through a biological nanopore.
Weigang Chen, Peng Zhang, Lifu Song, Jinsheng Yang, Changcai Han   +4 more
doaj   +1 more source