Results 11 to 20 of about 743,554 (284)

Nanopore sequencing in microgravity [PDF]

npj Microgravity, 2016
Abstract Rapid DNA sequencing and analysis has been a long-sought goal in remote research and point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological research and close monitoring of crew health, but spaceflight places stringent restrictions on the mass and volume of ...
Alexa B R McIntyre, Lindsay Rizzardi, Angela M Yu, Noah Alexander, Gail L Rosen, Douglas J Botkin, Sarah E Stahl, Kristen K John, Sarah L Castro-Wallace, Ken McGrath, Aaron S Burton, Andrew P Feinberg, Christopher E Mason   +12 more
openaire   +6 more sources

Nanopore DNA sequencing with MspA [PDF]

Proceedings of the National Academy of Sciences, 2010
Nanopore sequencing has the potential to become a direct, fast, and inexpensive DNA sequencing technology. The simplest form of nanopore DNA sequencing utilizes the hypothesis that individual nucleotides of single-stranded DNA passing through a nanopore will uniquely modulate an ionic current flowing through the pore, allowing the ...
Ian M, Derrington, Tom Z, Butler, Marcus D, Collins, Elizabeth, Manrao, Mikhail, Pavlenok, Michael, Niederweis, Jens H, Gundlach   +6 more
openaire   +3 more sources

Nanopore SimulatION – a raw data simulator for Nanopore Sequencing [PDF]

2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2018
Nanopore DNA sequencing enables the sequence determination of single DNA molecules up to 10,000 times longer than currently permitted by second-generation sequencing platforms. Nanopore sequencing gives real-time access to sequencing data and enables the detection of epigenetic modifications.
Christian Rohrandt, Nadine Kraft, Pay Gießelmann, Bjorn Brandl, Bernhard M. Schuldt, Ulrich Jetzek, Franz-Josef Müller   +6 more
openaire   +5 more sources

Nanopore Sequencing Technology: A Reliable Method for Pathogen Diagnosis in Elderly Patients with Community-Acquired Pneumonia [PDF]

Infection and Drug Resistance
Xiyue Zhang,1,* Jian Ye,2,* Limin Wang,1 Liuhai Zhang,1 Liusheng Wang,1 Hualiang Jin1 1Department of Respiratory Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, People’s Republic of China;
Zhang X, Ye J, Wang L, Zhang L, Wang L, Jin H   +5 more
doaj   +1 more source

Carbon nanopores for DNA sequencing: a review on nanopore materials

Chemical Communications, 2023
Herein, we review the recent progress and achievements in carbon nanopore sequencing based on materials, including the selection of carbon nanomaterials, technologies for nanopore formation, and future perspectives of carbon nanopore sequencing.
Jing Xu, Xin Jiang, Nianjun Yang
openaire   +4 more sources

Genome Analysis Methods using Long Read Nanopore Sequencing [PDF]

, 2021
Third-generation long-read technologies denote the latest progression in high throughput DNA and RNA sequence analysis. Complementing the widespread second-generation short-read platforms, long-read sequencing adds unique application opportunities by ...
Giesselmann, Pay, Gießelmann, P. ; https://orcid.org/   +1 more
core   +1 more source

Optimized Cas9-Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders. [PDF]

Adv Sci (Weinh)
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Lee S, Jung C, Kim M, Kim N, Hwang GH, Lee ST, Chu K, Lee SK, Kim HJ, Chae JH, Bae S, Moon J.   +11 more
europepmc   +2 more sources

Nanopore sequencing of ocean microbiomes [PDF]

, 2022
Ocean microbiomes are responsible for the majority of global primary production, and are crucial for global biogeochemical cycles. Eukaryotic phytoplankton contribute to the carbon cycle which is important for the climate, with polar communities making a
Langan, Emma
core   +4 more sources

Freshwater monitoring by nanopore sequencing [PDF]

eLife, 2020
ABSTRACT While traditional microbiological freshwater tests focus on the detection of specific bacterial indicator species, including pathogens, direct tracing of all aquatic DNA through metagenomics poses a profound alternative.
Urban, Lara, Holzer, Andre, Baronas, J Jotautas, Hall, Michael, Braeuninger-Weimer, Philipp, Scherm, Michael J, Kunz, Daniel J, Perera, Surangi N, Martin-Herranz, Daniel E, Tipper, Edward T, Salter, Susannah J, Stammnitz, Maximilian R   +11 more
openaire   +7 more sources

The Power of Using Novel Nanopore Sequencing Technology for Diagnosis, Genomic and Pathological Studies of Covid-19 [PDF]

E3S Web of Conferences, 2021
The novel coronavirus disease 2019 (COVID‐19), originally identified in December 2019 Wuhan, China, has propagated to worldwide pandemic, causing many cases of death and morbidity.
Du Chenghao
doaj   +1 more source