Results 11 to 20 of about 47,109 (297)

Nanopore sequencing in microgravity [PDF]

npj Microgravity, 2016
Abstract Rapid DNA sequencing and analysis has been a long-sought goal in remote research and point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological research and close monitoring of crew health, but spaceflight places stringent restrictions on the mass and volume of ...
Alexa B R McIntyre, Lindsay Rizzardi, Angela M Yu, Noah Alexander, Gail L Rosen, Douglas J Botkin, Sarah E Stahl, Kristen K John, Sarah L Castro-Wallace, Ken McGrath, Aaron S Burton, Andrew P Feinberg, Christopher E Mason   +12 more
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Nanopore DNA sequencing with MspA [PDF]

Proceedings of the National Academy of Sciences, 2010
Nanopore sequencing has the potential to become a direct, fast, and inexpensive DNA sequencing technology. The simplest form of nanopore DNA sequencing utilizes the hypothesis that individual nucleotides of single-stranded DNA passing through a nanopore will uniquely modulate an ionic current flowing through the pore, allowing the ...
Ian M, Derrington, Tom Z, Butler, Marcus D, Collins, Elizabeth, Manrao, Mikhail, Pavlenok, Michael, Niederweis, Jens H, Gundlach   +6 more
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Nanopore SimulatION – a raw data simulator for Nanopore Sequencing [PDF]

2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2018
Nanopore DNA sequencing enables the sequence determination of single DNA molecules up to 10,000 times longer than currently permitted by second-generation sequencing platforms. Nanopore sequencing gives real-time access to sequencing data and enables the detection of epigenetic modifications.
Christian Rohrandt, Nadine Kraft, Pay Gießelmann, Bjorn Brandl, Bernhard M. Schuldt, Ulrich Jetzek, Franz-Josef Müller   +6 more
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Carbon nanopores for DNA sequencing: a review on nanopore materials [PDF]

Chemical Communications, 2023
Herein, we review the recent progress and achievements in carbon nanopore sequencing based on materials, including the selection of carbon nanomaterials, technologies for nanopore formation, and future perspectives of carbon nanopore sequencing.
Jing Xu, Xin Jiang, Nianjun Yang
openaire   +4 more sources

Nanopore Sequencing Technology: A Reliable Method for Pathogen Diagnosis in Elderly Patients with Community-Acquired Pneumonia [PDF]

Infection and Drug Resistance
Xiyue Zhang,1,* Jian Ye,2,* Limin Wang,1 Liuhai Zhang,1 Liusheng Wang,1 Hualiang Jin1 1Department of Respiratory Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, People’s Republic of China;
Zhang X, Ye J, Wang L, Zhang L, Wang L, Jin H   +5 more
doaj   +2 more sources

DNA Sequencing by Hexagonal Boron Nitride Nanopore: A Computational Study [PDF]

Nanomaterials, 2016
The single molecule detection associated with DNA sequencing has motivated intensive efforts to identify single DNA bases. However, little research has been reported utilizing single-layer hexagonal boron nitride (hBN) for DNA sequencing.
Liuyang Zhang, Xianqiao Wang
doaj   +2 more sources

Matched Oxford Nanopore Technologies and Bisulfite Sequencing of the GM24385 Cell Line [PDF]

, 2022
One of the most widespread genomic modifications is 5-methylcytosine (5mC), which most frequently occurs at CpG dinucleotides. Compared to whole-genome bisulfite sequencing, the traditional method of 5mC detection, nanopore technology can offer many ...
Oxford Nanopore Technologies
core   +1 more source

Genome Analysis Methods using Long Read Nanopore Sequencing [PDF]

, 2021
Third-generation long-read technologies denote the latest progression in high throughput DNA and RNA sequence analysis. Complementing the widespread second-generation short-read platforms, long-read sequencing adds unique application opportunities by ...
Giesselmann, Pay, Gießelmann, P. ; https://orcid.org/   +1 more
core   +1 more source

Freshwater monitoring by nanopore sequencing [PDF]

eLife, 2020
ABSTRACT While traditional microbiological freshwater tests focus on the detection of specific bacterial indicator species, including pathogens, direct tracing of all aquatic DNA through metagenomics poses a profound alternative.
Urban, Lara, Holzer, Andre, Baronas, J Jotautas, Hall, Michael, Braeuninger-Weimer, Philipp, Scherm, Michael J, Kunz, Daniel J, Perera, Surangi N, Martin-Herranz, Daniel E, Tipper, Edward T, Salter, Susannah J, Stammnitz, Maximilian R   +11 more
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The potential and challenges of nanopore sequencing [PDF]

Nature Biotechnology, 2008
A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore. The nanopore provides a highly confined space within which single nucleic acid polymers can be analyzed at high throughput by one of a variety of means, and the perfect ...
Branton, Daniel, Pershin, Yuriy V, Deamer, David W, Ling, Xinsheng Sean, Wiggin, Matthew, Lindsay, Stuart, Krstic, Predrag S, Huang, Xiaohua, Jovanovich, Stevan B, Butler, Thomas, Soni, Gautam V, Schloss, Jeffery A, Riehn, Robert, Hibbs, Andrew, Tabard-Cossa, Vincent, Wanunu, Meni, Bayley, Hagan, Marziali, Andre, Ramsey, J Michael, Mastrangelo, Carlos H, Meller, Amit, Benner, Steven A, Oliver, John S, Garaj, Slaven, Di Ventra, Massimiliano   +24 more
openaire   +4 more sources