Results 171 to 180 of about 6,158,462 (316)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Student Unions and Activities Board of Governors Minutes, 2009-2010

, 2010
These minutes were scanned from bound volumes. Physical copies of these minutes are kept in the University of Minnesota Archives, and can be requested by contacting the University Archives directly.Student Unions and Activities Board of Governors. (2010).
Student Unions and Activities Board of Governors
core  

Association between the different basic activities of daily living on the Barthel index and community living, use of mobility aids, and the survival at 5 years. [PDF]

Front Public Health
Martín Moreno V, Pérez Rico E, Martín Fernández A, Hurtado Gallar J, Sánchez González I, Sánchez Rodríguez E, Martínez Sanz MI, Fernández Gallardo M, Marcos Guerra J, Cubero Sobrados MDC, Flórez Busto L, García Mateos A, Alonso Serna B, Vásquez Alay AL.   +13 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Student Unions and Activities Board of Governors Minutes, 2006-2007

, 2007
These minutes were scanned from bound volumes. Physical copies of these minutes are kept in the University of Minnesota Archives, and can be requested by contacting the University Archives directly.Student Unions and Activities Board of Governors. (2007).
Student Unions and Activities Board of Governors
core  

Development of semantic verbal fluency in children aged 2 to 5 and its relationship with participating in music activities. [PDF]

PLoS One
Torppa R, Looi V, Henttonen P, Pekkala S.   +3 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Student Unions and Activities Board of Governors Minutes, 2007-2008

, 2008
These minutes were scanned from bound volumes. Physical copies of these minutes are kept in the University of Minnesota Archives, and can be requested by contacting the University Archives directly.Student Unions and Activities Board of Governors. (2008).
Student Unions and Activities Board of Governors
core  

Viewpoint from facilities to communities: Breastfeeding promotion in Baby-Friendly Provinces in Türkiye. [PDF]

Int Breastfeed J
Aydoğmuş YH, Uyar H, Yalçın SS, Bağcı HH.   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source