Results 221 to 230 of about 7,818,688 (294)

Supporting Social Engagement in Long-Term Care Through Paired Socially Assistive Robot-Virtual Reality Activities for Older Adults with Cognitive Impairment and Apathy. [PDF]

Clin Interv Aging
Migovich M, Ghosh R, Khan N, Maxwell CA, Newhouse PA, Scharre DW, Tan A, Tate JA, Mion LC, Sarkar N.   +9 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Outdoor education on the mental health of Chinese children: a mini-review. [PDF]

Front Psychol
Li X, Zhong L.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The impact of aging, sex, and exercise on brain mitochondria. [PDF]

Front Aging
Zhang J, Darley-Usmar V, Li Y.
europepmc   +1 more source

Metabolite Profiling, Modulation of Glucose Metabolism and Antioxidant Activity Reveals the Protective Effect of Sulfated Polysaccharides From <i>Gracilaria gracilis</i> in Hepatic Tissues of Type 2 Diabetic Rats. [PDF]

Food Sci Nutr
Mpungose L, Olasehinde TA, Erukainure OL, Kumar A, Islam MS, Olaniran AO.   +5 more
europepmc   +1 more source