Results 41 to 50 of about 14,136,893 (299)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Power Quality Assessment and Optimization in FUZZY-Driven Healthcare Devices
IEEE AccessThe advent of FUZZY technology has revolutionized healthcare, empowering smarter medical devices and equipment. However, the successful operation of these FUZZY-driven systems is contingent on high power quality. This paper introduces an innovative FUZZY-
Dinesh Kumar Nishad +2 more
doaj +1 more source
Foods, 2023 Similar to genetically modified organisms (GMOs) produced by classical genetic engineering, gene-edited (GE) organisms and their derived food/feed products commercialized on the European Union market fall within the scope of European Union Directive 2001/
Marie-Alice Fraiture +9 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Scientific DataTaxonomic classification is crucial in identifying organisms within diverse microbial communities when using metagenomics shotgun sequencing. While second-generation Illumina sequencing still dominates, third-generation nanopore sequencing promises ...
Alexander Van Uffelen +5 more
doaj +1 more source
Exploring factors of stress level in parents of children with autistic spectrum disorder [PDF]
Specijalna Edukacija i Rehabilitacija, 2017 In addition to difficulties in social interaction and communication, children with autistic spectrum disorder (ASD) also exhibit behaviors that interfere with daily activities and are difficult to control, which can lead to disturbances in the household ...
Stanojević Nina +3 more
doaj
DESIGN OF A SURVEILLANCE SYSTEM FOR PREGNANCY AND ITS OUTCOMES IN RURAL NEPAL
Journal of Nepal Medical Association, 2003 Introduction Community trials in low-income countries require monitoring and evaluation systems. The requirements of a community surveillance system include coherent design, training, field supervision and reporting, as well as the need for a robust and ...
David Osrin +7 more
doaj +1 more source
An improved plant CRISPR-Cas9 system for generating Cas9-free multiplex mutants
Biotechnology & Biotechnological Equipment, 2021 CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas9 mediated gene editing systems have been used in a variety of organisms, including plants.
Jun-Li Wang +11 more
doaj +1 more source