Results 131 to 140 of about 1,947,838 (286)

Cognitive dysfunction, social participation, and performance of activities of daily living among a sub-urban community-dwelling older adults in Nigeria

Cogent Gerontology
Cognitive dysfunction (CF) in older adults significantly impacts activities of daily living (ADLs), social participation (SP), instrumental activities of daily living (IADLs), and overall quality of life. This cross-sectional study assessed CF, SP, ADLs,
Obiekwe Sochima Johnmark, Uzoamaka Nwakego Akobundu, Okwudili Precious Emuka, Akosile Christopher Olusanjo, Uchechukwu Martha Chukwuemeka, Ukamaka Gloria Mgbeojedo, Uchenna Prosper Okonkwo   +6 more
doaj   +1 more source

An Educational Pathway for Geriatric Home Caregivers [PDF]

, 2008
The establishment of a multi-tiered educational pathway for geriatric home caregivers would support efforts to meet the needs of an increasing number of community dwelling older adults who require assistance with activities of daily living, while ...
Beth C. Vaughan-Wrobel, Sherry White
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

How do Adolescents Spell Time Use? [PDF]

We investigate how household disadvantage affects the time use of 15-18 year-olds using 2003- 2006 data from the American Time Use Survey. Applying competing-risk hazard models, we distinguish between the incidence and duration of activities and ...
Charlene M. Kalenkoski, David C. Ribar, Leslie S. Stratton   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Status of Daily Living Activities among Older People in Maku

Elderly Health Journal, 2016
Introduction: One of the most popular methods for evaluating old people’s health condition is to assess their functional practice. The aim of this study was to assess the status of daily living activities among the older people of Maku, Iran ...
Mehdi Abbasian, Faezeh Ghalichi, Batol Ahmadi, Paria Ghasemzadeh, Ebrahim Esmaeilpour, Hossein Matlabi   +5 more
doaj  

Muscle co‐activation across activities of daily living in individuals with knee osteoarthritis [PDF]

, 2019
Astephen JL, Astephen Wilson JL, Bae WC, Baliunas A, Baratta R, Bouchouras G, Brunner R, Burden AM, Childs JD, Collins A, DeMont RG, DeMont RG, Flaxman TE, Flaxman TE, Heiden TL, Hermens HJ, Hodges PW, Hopkins JT, Hortobágyi T, Hubley‐Kozey C, Hubley‐Kozey CL, Hubley‐Kozey CL, Lewek MD, Lewek MD, Lewek MD, Lewek MD, Lloyd DG, MacWilliams BA, Metcalfe AJ, Mills K, Pallant J, Patsika G, Patsika G, Ramsey DK, Roos EM, Rudolph KS, Rudolph KS, Rutherford DJ, Schipplein OD, Schmitt LC, Soderberg GL, Sturnieks DL, Tennant LM, Thabane L, Vera‐Garcia FJ, Winby CR, Zeni JA   +46 more
core   +2 more sources

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Impact of Kegel Exercise on Brink Scale and Activities of Daily Life(ADLs) in Patients of Cystocele

Journal of Rawalpindi Medical College, 2013
Background : To study the impact of Kegel exercise on Brink scale and ADLs (Activities of daily life scale) in patients of Cystocele Methods: In this randomized control trial 50 patients of cystocoele (25 each) were divided into two groups.
Taqdees Naqaish
doaj