Activity - Open Access .click

Results 121 to 130 of about 10,307,474 (313)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

Activity - Binary Code

, 2019
A Binary Code activity and worksheet for CS0 students.
Domanski, Robert J
core

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

Understanding Unemployment Statistics (Activity)

, 2020
When you see unemployment statics in the news – such as, “unemployment rises to 11%” – are you certain that you are interpreting them correctly?
Martin, Tom
core

Correction: Characterizing children’s eating patterns: does the choice of eating occasion definition matter?

International Journal of Behavioral Nutrition and Physical Activity, 2023
Rebecca M. Leech +5 more
doaj +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

Prohibition of Competitive Activities for Members of Housing Cooperative Councils and Boards as well as Consequences of Non-Compliance with the Prohibition

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej, 2019
The article refers to the problem of prohibition of competition imposed on the members of the board of directors and the supervisory board of the cooperative. The Author analyzes the concepts of "competitive business" and "competitive activity" and their
Anna Wilk
doaj +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

Speed Dating Peer Review Activity

, 2021
Peer Review of student writing in a fully online, synchronous learning environment can be challenging. By drawing on the principles of speed dating, this activity meets 3 goals for fostering student success: fosters student-student engagement, encourages
Gianoulis, Gloria, Rocco, Susan
core

A systematic review of occupation- and activity-based health management interventions for adult patients with severe mental disorders

Journal of Education and Health Promotion
BACKGROUND: Considering the negative effects of severe mental disorders (SMDs) on the patient’s social and occupational functioning and general health, besides accumulating evidence on the effectiveness of occupation- and activity-based health management
Elham Nasiri +3 more
doaj +1 more source

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