Results 151 to 160 of about 18,606,965 (308)
a cross-entropy based multiagent approach for multiclass activity chain modeling and simulation [PDF]
This paper attempts to model complex destination-chain, departure time and route choices based on activity plan implementation and proposes an arc-based cross entropy method for solving approximately the dynamic user equilibrium in multiagent-based ...
Jean-Patrick Lebacque, Tai-Yu Ma
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016 The article discusses a heuristic approach to the formation of professional competence of future engineers chemists when studying a foreign language taking into account the trends of modern society’s development.
Irina V. Vlasova
doaj
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Інформаційні технології і засоби навчання, 2010 In the paper the scientific approaches to modeling of innovation educational environment of a general educational institution – system (analysis of object, process and result of modeling as system objects), activity (organizational and psychological ...
Anzhelika D. Tsymbalaru
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2015 Purpose: Evidence suggests that physical inactivity and sedentary time (ST) are independent risk factors for poor health. While there have been many successful interventions targeting these lifestyle behaviours, few studies have examined the relationship
Rosenkranz, Richard R. (R15136) +3 more
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source