Results 31 to 40 of about 376,807 (240)

FUNCTIONAL CAPACITY AND LEVEL OF PHYSICAL ACTIVITY IN CENTENARIANS OF FLORIANÓPOLIS, BRAZIL

Journal of Physical Education, 2017
This study aimed to compare the level of physical activity and functional capacity of centenarians from Florianopolis, Brazil. To measure the level of physical activity and functional capacity, pedometer and the Katz scale, respectively, were used. Study
Inês Amanda Streit, Artur Rodrigues Fortunato, Eduardo Hauser, Giovana Zarpellon Mazo   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Assessment of retired elderly’s people autonomy and its affecting factors in Rasht

Journal of Holistic Nursing and Midwifery, 2011
Introduction: In elderly, autonomy is threatened due to physical and mental disability. This ‎disability in activity of daily living is a chronic condition that causes cost disbursement in ‎society and reduce older people s quality of life. ‎
Nasrin Masoumi, Shirin Jafroudi, Atefeh Ghanbari Khanghah, Ehsan Kazemnejad Leili   +3 more
doaj  

Effectiveness of Cognitive Function and Activity of Daily Living (ADL) on Elderly Independence

Lentera Perawat
Aging is a natural process followed by physical and behavioural changes. All individuals will experience the process of growing old and old age is the final stage of human life, where there is a gradual physical, mental and social decline.
Andre Utama Saputra, Nila Alfa Fauziah, Jupiter Eko Saputra   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Relationship Between Mental State and Functional Status in Elderly Residents of Kahrizak

Sālmand, 2010
Objectives: The current study was performed to investigate the relationship between mental impairment and each component of activity of daily living (ADL) in elderly residents of the Kahrizak Charity Foundation. Methods & Materials: Standardized Iranian
Hadi Kazemi, Sima Ghasemi, Farshad Sharifi, Hossein Fakhrzadeh, Maryam Ghaderpanahi, Mojde Mirarefin, Mahshid Foroughan, parvaneh Mohammadkhani   +7 more
doaj